Shuichi Kaneko
Kanazawa University
900 Papers
5.7K Citations
Shuichi Kaneko is an academic researcher from Kanazawa University. The author has contributed to research in topics: Hepatocellular carcinoma & Medicine. The author has an hindex of 86, co-authored 842 publications. Previous affiliations of Shuichi Kaneko include Kaneka Corporation & Tottori University.
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Papers
Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma
TL;DR: This work developed a novel framework to identify distinct patterns of gene coexpression networks and inflammation-related modules from genome-scale microarray data upon viral infection, and further classified them into oncogenic and dysfunctional ones and revealed two types of driving modules related to infection for carcinogenesis in HBV and HCV.
MCP-1/CCR2-dependent loop for fibrogenesis in human peripheral CD14-positive monocytes
Norihiko Sakai,Takashi Wada,Kengo Furuichi,Kazuaki Shimizu,Satoshi Kokubo,Akinori Hara,Junya Yamahana,Toshiya Okumura,Kouji Matsushima,Hitoshi Yokoyama,Shuichi Kaneko +10 more
TL;DR: The present study demonstrated that human peripheral CD14‐positive Mo contribute directly to fibrogenesis by a MCP‐1/CCR2‐dependent amplification loop, suggesting that fibrogenic processes in Mo regulated by MCP1/ CCR2 may be novel, therapeutic targets for combating organ fibrosis.
Endogenous muscle atrophy F-box is involved in the development of cardiac rupture after myocardial infarction.
Soichiro Usui,Akio Chikata,Osamu Takatori,Shin Ichiro Takashima,Oto Inoue,Takeshi Kato,Hisayoshi Murai,Hiroshi Furusho,Ayano Nomura,Daniela Zablocki,Shuichi Kaneko,Junichi Sadoshima,Masayuki Takamura +12 more
TL;DR: It is concluded that MAFbx plays an important role in the mediation of excessive inflammation, including neutrophil infiltration, inflammasome formation, and production of proinflammatory cytokines through the activation of Nfkb, promoting cardiac rupture after MI.
Serum C16:1n7/C16:0 ratio as a diagnostic marker for non‐alcoholic steatohepatitis
Kazutoshi Yamada,Eishiro Mizukoshi,Takuya Seike,Rika Horii,Takeshi Terashima,Noriho Iida,Masaaki Kitahara,Hajime Sunagozaka,Kuniaki Arai,Tatsuya Yamashita,Masao Honda,Toshinari Takamura,Kenichi Harada,Shuichi Kaneko +13 more
TL;DR: The serum fatty acids composition is investigated and the possibility of using the serum fatty acid composition as a diagnostic marker of NASH is evaluated.
Cost-Effectiveness of Lenvatinib in the Treatment of Patients With Unresectable Hepatocellular Carcinomas in Japan: An Analysis Using Data From Japanese Patients in the REFLECT Trial.
Shunya Ikeda,Masatoshi Kudo,Namiki Izumi,Masahiro Kobayashi,Mie Azuma,Genevieve Meier,Janice Pan,Mika Ishii,Shuichi Kaneko +8 more
TL;DR: In this article, a cost-effectiveness analysis of lenvatinib versus sorafenib for first-line treatment of unresectable hepatocellular carcinoma (HCC) in Japan was conducted.