Shu-Yu Wang
Zhengzhou University
6 Papers
Shu-Yu Wang is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Tubulin & Chemistry. The author has an hindex of 2, co-authored 4 publications.
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Papers
Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway.
Jian Song,Qiu-Lei Gao,Bo-Wen Wu,Ting Zhu,Xin-Xin Cui,Cheng-Jun Jin,Shu-Yu Wang,Sheng-Hui Wang,Dong-Jun Fu,Hong-Min Liu,Sai-Yang Zhang,Yan-Bing Zhang,Yongchun Li +12 more
TL;DR: Compound F10 was the first to be reported as a new anticancer agent in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway and binding tightly into the colchicine binding site of β-tubulin.
50
Progress of tubulin polymerization activity detection methods
TL;DR: In this paper, the biological activity detection methods of tubulin polymerization inhibitors are reviewed and a theoretical basis for the further study and selection of methods for tubulin inhibitors is provided.
24
Review of NEDDylation inhibition activity detection methods
Shu-Yu Wang,Xu Liu,Yuan Liu,Hong-Yu Zhang,Yan-Bing Zhang,Chong Liu,Jian Song,Jin-Bo Niu,Sai-Yang Zhang +8 more
TL;DR: This review will provide an up-to-date and comprehensive review of the methods for detecting NEDDylation activity that will contribute to NEDdylation inhibitor development.
8
Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities.
Jian-Ying Song,Shu-Yu Wang,Xiao Wang,Mei-Qi Jia,Xin-Yi Tian,X. Fu,Cheng-Yun Jin,Sai-Yang Zhang +7 more
TL;DR: Wang et al. as discussed by the authors designed and synthesized a new coumarin-dihydroquinoxalone derivative, MY-673, and evaluated its anticancer potency in vitro and in vivo.
7
Identification of key genes and pathway related to chemoresistance of small cell lung cancer through an integrative bioinformatics analysis
Fan-Rui Zeng,Xu Zhou,Lingzao Zeng,Jian Sun,Fen He,Wei-Jia Mo,Yang Wen,Shu-Yu Wang,Qin Liu,Lin-Lang Guo +9 more
TL;DR: The top 10 upregulated DELs containing NCRNA00173 may be involved in the regulation of drug resistance in SCLC and may regulate the genes related to the mTOR signaling pathway.