Shu Wang
Sichuan University
25 Papers
123 Citations
Shu Wang is an academic researcher from Sichuan University. The author has contributed to research in topics: Bulbus fritillariae cirrhosae & Medicine. The author has an hindex of 12, co-authored 20 publications.
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Papers
Antitussive, expectorant and anti-inflammatory activities of four alkaloids isolated from Bulbus of Fritillaria wabuensis
TL;DR: Evidence is provided for Bulbus Fritillaria Cirrhosae to be used as an antitussive and expectorant Traditional Chinese Medicine (TCM) drug and the structures of the four alkaloids isolated from BFW were confirmed.
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Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae Cirrhosae
TL;DR: The results confirmed that the four alkaloids imperialine, chuanbeinone, verticinone and verticine may be the active ingredients of the Bulbus F. Cirrhosae (BFC).
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The total alkaloid fraction of bulbs of Fritillaria cirrhosa displays anti-inflammatory activity and attenuates acute lung injury.
TL;DR: TAF can inhibit acetic acid-induced capillary permeability accentuation, carrageenan-induced paw edema, cotton pellet-induced granuloma formation, suppress inflammatory cells recruitment and cytokine production in the bronchoalveolar lavage fluid from LPS-induced ALI mice, and attenuate pathological changes in the lung tissues of ALi mice.
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Imperialine and Verticinone from Bulbs of Fritillaria wabuensis Inhibit Pro-inflammatory Mediators in LPS-stimulated RAW 264.7 Macrophages.
TL;DR: It is demonstrated that verticinone or imperialine could dose-dependently inhibit nitric oxide production and also suppress inducible nitricoxide synthase and cyclooxygenase-2 expressions and suppress the production of pro-inflammatory cytokines in a dose dependent manner.
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Isosteroid alkaloids from Fritillaria cirrhosa bulbus as inhibitors of cigarette smoke-induced oxidative stress.
TL;DR: Findings for the first time demonstrated that F. cirrhosa bulbus may play a protective role in cellular oxidative stress by activating Nrf2-mediated antioxidant pathway and suggested that it might be a promising therapeutic treatment for the prevent of oxidative stress-related diseases.
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