Shreeja Biswas
6 Papers
Shreeja Biswas is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 4 publications.
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Papers
Host inducible-HSP70A1A is an irresistible drug target to combat SARS-CoV2 infection and pathogenesis
P. Joshi,S. Garg,Shailendra Mani,Kamini Jakhar,Manisha Marothia,Rumaisha Shoaib,Shreeja Biswas,Jhalak Singhal,Ankita Behl,Amandeep Kaur Kahlon,Maxim Shevtsov,Pramod Garg,Shailja K. J. Singh,Anand Ranganathan +13 more
TL;DR: In this article , the authors demonstrate that the SARS-CoV-2 virus exploits the host HSP70 chaperone for its entry and propagation and blocking it can combat the infection.
Dynamic Palmitoylation of Red Cell Membrane Proteins Governs Susceptibility to Invasion by the Malaria Parasite, Plasmodium falciparum.
Geeta Kumari,D A B Rex,Sangam Goswami,Soumyadeep Mukherjee,Shreeja Biswas,Preeti Maurya,Ravi Jain,S. Garg,T. S. Keshava Prasad,Soumya Pati,Sivaprakash Ramalingam,Narla Mohandas,Shailja Singh +12 more
TL;DR: A significant reduction in merozoite contact with the RBC membrane and a consequent decrease in parasite invasion following 2-BMP treatment demonstrated that palmitoylation does indeed regulate RBC susceptibility to parasite invasion.
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Targeting PfProhibitin 2 - Hu-Hsp70A1A complex as a unique approach towards malaria vaccine development
Manisha Marothia,Ankita Behl,Preeti Maurya,Monika Saini,Rumaisha Shoaib,S. Garg,Geeta Kumari,Shreeja Biswas,Akshay Munjal,Sakshi Anand,Amandeep Kaur Kahlon,Pragya Gupta,Saurav Biswas,Bidhan Goswami,Haider Thaer Abdulhameed Almuqdadi,Ipsita Pal Bhowmick,Maxim Shevtsov,Sivaprakash Ramalingam,Anand Ranganathan,Shailja K. J. Singh +19 more
TL;DR: Researchers identify PfProhibitin 2-Hu-Hsp70A1A complex as a potential malaria vaccine target, leveraging its unique interaction with erythrocyte receptors to inhibit parasite invasion and mitigate disease pathology in host erythrocytes.
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Decoding the multifaceted role of erythrocyte PMCA4b in oxidative stress-mediated malaria protection and artemisinin resistance
Priya Agrohi,S. Garg,Shreeja Biswas,Preeti Maurya,Vijay Kumar,Jyoti Sharma,Bidhan Goswami,Samir Kumar Sil,Mrigendra Pal Singh,Sunil Kumar Chand,Sneh Shalini,O. P. Singh,G. Dhangadamajhi,Neelima Mishra,Sivaprakash Ramalingam,Prashant Kumar Mallick,Shailja K. J. Singh +16 more
Chaperonin activity of Plasmodium prefoldin complex is essential to guard proteotoxic stress response and presents a new target for drug discovery
Rumaisha Shoaib,Vikas Kumar,S. Garg,Monika Saini,Jyoti Kumari,Preeti Maurya,Aashima Gupta,Nutan Gupta,Harshita Singh,Pritee Verma,Ravi Jain,Shreeja Biswas,Ankita Behl,Mohammad Abid,Shailja Singh +14 more
TL;DR: This study functionally characterize the Plasmodium falciparum prefoldins (PfPFD1-6), a hexameric co-chaperone complex, for their role in protein homeostasis and provides novel virtues towards understanding the role of PfPFDs in regulating proteinHomeostasis.