Shosuke Kitamura
Hiroshima University
14 Papers
59 Citations
Shosuke Kitamura is an academic researcher from Hiroshima University. The author has contributed to research in topics: Hepatitis B virus & Internal medicine. The author has an hindex of 6, co-authored 12 publications.
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Papers
HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice
Masataka Tsuge,Nobuhiko Hiraga,Rie Akiyama,Sachi Tanaka,Miyuki Matsushita,Fukiko Mitsui,Hiromi Abe,Shosuke Kitamura,Tsuyoshi Hatakeyama,Takashi Kimura,Daiki Miki,Nami Mori,Michio Imamura,Shoichi Takahashi,C. Nelson Hayes,Kazuaki Chayama +15 more
TL;DR: It was concluded that the HBx protein is indispensable for HBV replication and could be a target for antiviral therapy.
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Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review
Masanori Ito,Shunsuke Takata,Masana Tatsugami,Yoshihiro Wada,Shinobu Imagawa,Yoshiaki Matsumoto,Akemi Takamura,Shosuke Kitamura,Taiji Matsuo,Shinji Tanaka,Ken Haruma,Kazuaki Chayama +11 more
TL;DR: Considering the biological nature of cancer cell proliferation, a sufficiently long-term follow-up may clarify the effect of eradication therapy on inhibition of the development (not discovery) of Gastric cancer and reduction of gastric cancer-related mortality.
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Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice
Nobuhiko Hiraga,Michio Imamura,Tsuyoshi Hatakeyama,Shosuke Kitamura,Fukiko Mitsui,Shinji Tanaka,Masataka Tsuge,Shoichi Takahashi,Hiromi Abe,Toshiro Maekawa,Hidenori Ochi,Chise Tateno,Katsutoshi Yoshizato,Katsutoshi Yoshizato,Takaji Wakita,Kazuaki Chayama +15 more
TL;DR: No interference between the two hepatitis viruses exists in the liver in the absence of hepatitis, and the mechanisms of IFN resistance of the two viruses target different areas of the IFN system.
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G to A hypermutation of TT virus.
Masataka Tsuge,Chiemi Noguchi,Rie Akiyama,Miyuki Matsushita,Kana Kunihiro,Sachi Tanaka,Hiromi Abe,Fukiko Mitsui,Shosuke Kitamura,Tsuyoshi Hatakeyama,Takashi Kimura,Daiki Miki,Nobuhiko Hiraga,Michio Imamura,Shoichi Takahashi,C. Nelson Hayses,Kazuaki Chayama +16 more
TL;DR: The results show that hypermutated TTV exist in healthy individuals and HBV carriers and that TTV genomes were susceptible to immune reaction directed to HBV by interacting with APOBEC3 proteins.
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Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy.
Shosuke Kitamura,Masataka Tsuge,Tsuyoshi Hatakeyama,Hiromi Abe,Michio Imamura,Nami Mori,Hiromi Saneto,Tomokazu Kawaoka,Fukiko Mitsui,Nobuhiko Hiraga,Shintaro Takaki,Yoshiiku Kawakami,Hiroshi Aikata,Shoichi Takahashi,Waka Ohishi,Hidenori Ochi,C. Nelson Hayes,Kazuaki Chayama +17 more
TL;DR: Results indicate that analyses of aa substitutions in both the core region and the ISDR are useful for predicting the effectiveness of combination therapy, and could help to avoid therapy exposure for patients who have a low probability of SVR.
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