Shiro Ozasa
Kumamoto University
24 Papers
25 Citations
Shiro Ozasa is an academic researcher from Kumamoto University. The author has contributed to research in topics: Medicine & Duchenne muscular dystrophy. The author has an hindex of 9, co-authored 20 publications.
Chat about Author
Papers
Viltolarsen in Japanese Duchenne muscular dystrophy patients: A phase 1/2 study.
Hirofumi Komaki,Yasuhiro Takeshima,Tsuyoshi Matsumura,Shiro Ozasa,Michinori Funato,Eri Takeshita,Yasuyuki Iwata,Hiroyuki Yajima,Yoichi Egawa,Takuya Toramoto,Masaya Tajima,Shin'ichi Takeda +11 more
TL;DR: The novel morpholino antisense oligonucleotide viltolarsen targets exon 53 of the dystrophin gene, and could be an effective treatment for patients with Duchenne muscular dystrophy.
75
Presynaptic Dysfunction in Neurons Derived from Tay-Sachs iPSCs.
Kozo Matsushita,Tadahiro Numakawa,Haruki Odaka,Ryutaro Kajihara,Minami Soga,Shiro Ozasa,Kimitoshi Nakamura,Hiroshi Mizuta,Takumi Era +8 more
TL;DR: It is demonstrated that NPCs and mature neurons derived from TSD-iPSCs are potentially useful cellular models of TSD and are useful for investigating the efficacy of drug candidates in the future.
21
Newborn screening for spinal muscular atrophy in Japan: One year of experience
Takaaki Sawada,Jun Kido,Keishin Sugawara,Shinichiro Yoshida,Shiro Ozasa,Keiko Nomura,Kentaro Okada,Natsumi Fujiyama,Kimitoshi Nakamura +8 more
TL;DR: In this article , the authors report their experience with the NBS program for SMA and discuss an issue to be approached in the future, as well as the issue of newborn screening.
20
Immobility reduces muscle fiber necrosis in dystrophin deficient muscular dystrophy.
Shigemi Kimura,Makoto Ikezawa,Keiko Nomura,Kaori Ito,Shiro Ozasa,Hiroe Ueno,Kowasi Yoshioka,S. Yano,T. Yamashita,M. Matuskura,Teruhisa Miike +10 more
TL;DR: The results show that the restriction of excessive exercise is important for dystrophin deficiency disease, on the first case of Becker muscular dystrophy coinciding with spina bifida.
15
Natural history of Becker muscular dystrophy: a multicenter study of 225 patients.
Akinori Nakamura,Tsuyoshi Matsumura,Katsuhisa Ogata,Madoka Mori-Yoshimura,Eri Takeshita,Koichi Kimura,Takahiro Kawashima,Yui Tomo,Hajime Arahata,Daigo Miyazaki,Yasuhiro Takeshima,Toshiaki Takahashi,Keiko Ishigaki,Satoshi Kuru,Akiko Wakisaka,Hiroyuki Awano,Michinori Funato,Tatsuharu Sato,Yoshiaki Saito,Hiroto Takada,Kazuma Sugie,Michio Kobayashi,Shiro Ozasa,Tatsuya Fujii,Yoshihiro Maegaki,Hideki Oi,Hisateru Tachimori,Hirofumi Komaki +27 more
TL;DR: The clinical involvement of skeletal, respiratory, cardiac, and central nervous systems in patients with BMD, as well as genotype–phenotype relationships are investigated.
9