Shinsuke Chida
Akita University
6 Papers
22 Citations
Shinsuke Chida is an academic researcher from Akita University. The author has contributed to research in topics: Phosphatidylinositol & Excitatory postsynaptic potential. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Shinsuke Chida include Gunma University.
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Papers
The PtdIns(3,4)P 2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
Junko Sasaki,Satoshi Kofuji,Satoshi Kofuji,Reietsu Itoh,Reietsu Itoh,Toshihiko Momiyama,Kiyohiko Takayama,Haruka Murakami,Haruka Murakami,Shinsuke Chida,Shinsuke Chida,Yuko Tsuya,Yuko Tsuya,Shunsuke Takasuga,Shunsuke Takasuga,Satoshi Eguchi,Satoshi Eguchi,Ken Asanuma,Ken Asanuma,Yasuo Horie,Kouichi Miura,Elizabeth M Davies,Christina Anne Mitchell,Masakazu Yamazaki,Hirokazu Hirai,Tadaomi Takenawa,Akira Suzuki,Akira Suzuki,Takehiko Sasaki,Takehiko Sasaki +29 more
TL;DR: INPP4A represents the first signalling protein with a function in neurons to suppress excitotoxic cell death and thereby maintains the functional integrity of the brain, and provides insight into the unique aspects and physiological significance of PtdIns(3,4)P2 metabolism.
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Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner.
TL;DR: It is shown that Man1Δ/Δ embryos exhibit abnormal heart morphogenesis including the looping abnormality and results suggest that Man 1 regulates LR asymmetry by controlling Nodal signaling in a node‐independent manner.
22
Ship1 deletion enhances ros production and decreases survival of the s. aureus infected mice
Shinsuke Chida,Reietsu Itoh,Satoshi Kofuji,Satoshi Eguchi,Shunsuke Takasuga,Junko Sasaki,Takehiko Sasaki +6 more
- 30 Mar 2013
TL;DR: The results suggest that SHIP1 controls appropriate host defenses against S. aureus infections in mice, and enhanced ROS production as well as the bacterial killing capability of neutrophils.
Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine
Shunsuke Takasuga,Yasuo Horie,Junko Sasaki,Ge-Hong Sun-Wada,Nobuyuki Kawamura,Ryota Iizuka,Katsunori Mizuno,Satoshi Eguchi,Satoshi Kofuji,Hirotaka Kimura,Masakazu Yamazaki,Chihoko Horie,Eri Odanaga,Yoshiko Sato,Shinsuke Chida,Kenji Kontani,Akihiro Harada,Toshiaki Katada,Akira Suzuki,Yoh Wada,Hirohide Ohnishi,Takehiko Sasaki +21 more
TL;DR: The data demonstrate that PIPKIII is required for the structural and functional integrity of two different types of polarized epithelial cells and suggest that PtdIns(3,5)P2 metabolism is an unexpected and critical link between membrane trafficking in intestinal epithelial Cells and the pathogenesis of inflammatory bowel disease.