Shinichi Yachida
Johns Hopkins University
79 Papers
428 Citations
Shinichi Yachida is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 25, co-authored 51 publications. Previous affiliations of Shinichi Yachida include Kagawa University.
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Papers
Validation of risk assessment scoring systems for an audit of elective surgery for gastrointestinal cancer in elderly patients: An audit
Hisao Wakabayashi,Takanori Sano,Shinichi Yachida,Keiichi Okano,Kunihiko Izuishi,Yasuyuki Suzuki +5 more
TL;DR: Both the POSSUM and P-POSSUM over-predicted the morbidity and mortality in elective gastrointestinal surgery for malignant tumors in elderly patients, but if a surgical unit makes appropriate calculations using its own patient series and updates these equations, the PossUM system can be useful in the risk assessment for surgery in elderly Patients.
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Improved microcirculatory effect of D-allose on hepatic ischemia reperfusion following partial hepatectomy in cirrhotic rat liver.
Mohammad Akram Hossain,Hisao Wakabayashi,Kunihiko Izuishi,Keiichi Okano,Shinichi Yachida,Masaaki Tokuda,Ken Izumori,Hajime Maeta +7 more
TL;DR: D-allose, one of the rare sugars produced from D-psicose, has been shown to be effective against reperfusion injury after ischemia and partial hepatectomy in cirrhotic rat liver by improving remnant liver blood flow and survival rates, and decreasing liver enzyme levels and liver tissue injury levels.
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Neutrophil Elastase Inhibitor (Sivelestat) Preserves Antitumor Immunity and Reduces the Inflammatory Mediators Associated with Major Surgery
Shintaro Akamoto,Keiichi Okano,Takanori Sano,Shinichi Yachida,Kunihiko Izuishi,Hisashi Usuki,Hisao Wakabayashi,Yasuyuki Suzuki +7 more
TL;DR: The perioperative administration of sivelestat was suggested to reduce surgical stress by decreasing the cytokine release and preserving the antitumor immunity.
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Immunohistochemically detected expression of p27(Kip1) and Skp2 predicts survival in patients with intrahepatic cholangiocarcinomas.
Nozomi Hashimoto,Shinichi Yachida,Keiichi Okano,Hisao Wakabayashi,Katsumi Imaida,Kazutaka Kurokohchi,Tsutomu Masaki,Hisoka Kinoshita,Masahiro Tominaga,Tetsuo Ajiki,Yonson Ku,Takehiro Okabayashi,Kazuhiro Hanazaki,Makoto Hiroi,Sadanobu Izumi,Shohei Mano,Setsuo Okada,Yukihiko Karasawa,Takashi Maeba,Yasuyuki Suzuki +19 more
TL;DR: The results suggest that low p27Kip1 and high Skp2 expression are associated with aggressive tumor behavior, and these cell-cycle regulators are useful markers to predict outcome of patients with ICC-MF.
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Establishment and characterization of a new cell line, A99, from a primary small cell carcinoma of the pancreas.
Shinichi Yachida,Yi Zhong,Raul Patrascu,Meghan B. Davis,Laura Morsberger,Constance A. Griffin,Ralph H. Hruban,Daniel A. Laheru,Christine A. Iacobuzio-Donahue +8 more
TL;DR: A99 is the first cell line reported to be derived from a primary SCC of the pancreas, and may serve as a useful model system for studying the cell biology of this rare cancer or for evaluating novel targeted agents in preclinical models.