Shinichi Yachida
Johns Hopkins University
79 Papers
428 Citations
Shinichi Yachida is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 25, co-authored 51 publications. Previous affiliations of Shinichi Yachida include Kagawa University.
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Papers
The role of prostaglandins in liver ischemia-reperfusion injury.
Mohammad Anwar Hossain,Hisao Wakabayashi,Kunihiko Izuishi,K. Okano,Shinichi Yachida,H. Maeta +5 more
TL;DR: Prostaglandins confer their protective effects on IR-injured livers mainly by inhibiting the generation of reactive oxygen species, preventing leukocyte migration, reducing the synthesis or production of membrane degradation products, improving hepatic insulin and lipid metabolism, and regulating the production of inflammatory cytokines and cell adhesion molecules.
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A simple and safe pancreas transection using a stapling device for a distal pancreatectomy.
Keiichi Okano,Keitarou Kakinoki,Shinichi Yachida,Kunihiko Izuishi,Hisao Wakabayashi,Yasuyuki Suzuki +5 more
TL;DR: Findings support the advantages of using a stapler closure in distal pancreatectomy, considered to be a simple and safe alternative to the standard suture closure technique.
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Pilot feasibility study of neoadjuvant chemoradiotherapy with S-1 in patients with locally advanced gastric cancer featuring adjacent tissue invasion or JGCA bulky N2 lymph node metastases.
Tatsushi Inoue,Shinichi Yachida,Hisashi Usuki,Tomoki Kimura,Masanobu Hagiike,Keiichi Okano,Yasuyuki Suzuki +6 more
TL;DR: The present regimen seems to be feasible and safe as a treatment for locally advanced gastric cancers featuring adjacent tissue invasion or JGCA bulky N2 disease and should now be tested using the new tumor, node, metastasis staging system in a large clinical trial.
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Long-term survival after resection for small cell carcinoma of the esophagus
Shinichi Yachida,Kohtaroh Matsushita,Hisashi Usuki,Hideki Wanibuchi,Takashi Maeba,Hajime Maeta +5 more
TL;DR: This report describes the rare case of a patient with esophageal small cell carcinoma who was completely cured and suggests that radical operations should be considered for future patients if curative resection can be expected.
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Leveraging explainable AI for gut microbiome-based colorectal cancer classification
Ryza Rynazal,Kota Fujisawa,Hirotsugu Shiroma,Felix Salim,Sayaka Mizutani,Satoshi Shiba,Shinichi Yachida,Takuji Yamada +7 more
TL;DR: The potential of Shapley Additive Explanations (SHAP) for a more personalized CRC biomarker identification is investigated and analyses of five independent datasets show that this method can even separate CRC subjects into subgroups with distinct CRC probabilities and bacterial biomarkers.
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