Shinichi Yachida
Johns Hopkins University
79 Papers
428 Citations
Shinichi Yachida is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 25, co-authored 51 publications. Previous affiliations of Shinichi Yachida include Kagawa University.
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Papers
The pathology and genetics of metastatic pancreatic cancer.
TL;DR: Emerging data from a variety of investigators now indicate that overexpression of EphA2, loss of DPC4 and MKK4, and aberrant activation of the Hedgehog signaling pathway are associated with metastatic propensity of pancreatic cancers, providing novel therapeutic targets for the most lethal stage of this disease.
Morphological and functional alterations to sinusoidal endothelial cells in the early phase of endotoxin-induced liver failure after partial hepatectomy in rats
TL;DR: The morphological and functional alterations of SECs precede necrotic changes in hepatocytes and SECs in endotoxin-induced liver failure after partial hepatectomy, which is characterized pathologically by massive hepatic necrosis.
Association between Diet and Fusobacterium nucleatum in the Feces of Healthy Adults: A hospital-based cross-sectional study.
Nobuhiro Narii,Ling Zha,Tomotaka Sobue,Tetsuhisa Kitamura,Satoshi Shiba,Sayaka Mizutani,Takuji Yamada,Shinichi Yachida +7 more
TL;DR: In this paper, the authors evaluated the association between various dietary factors and fecal Fusobacterium nucleatum in healthy adults without a history of colorectal cancer or precancerous lesions.
Significance of fluorodeoxyglucose PET imaging in the diagnosis of malignancies in patients with biliary stricture.
Hisao Wakabayashi,Shintaro Akamoto,Shinichi Yachida,Keiichi Okano,Kunihiko Izuishi,Yoshihiro Nishiyama,Hajime Maeta +6 more
TL;DR: In diagnosing malignant diseases in patients with biliary stricture, FDG-PET was superior to CT examination in both sensitivity and specificity, and superior to cytological examination of the bile in sensitivity.
Measurement of serum hyaluronate as a predictor of human liver failure after major hepatectomy.
Shinichi Yachida,Hisao Wakabayashi,Yasutaka Kokudo,Fuminori Goda,Setsuo Okada,Takashi Maeba,Hajime Maeta +6 more
TL;DR: Serum hyaluronate levels were significantly elevated, in line with the degree of severity of the underlying chronic liver disorder, and correlated well with the portal venous pressure and the hypertrophic ratio of the left lobe subsequent to portal embolization.