12 Papers
21 Citations
Shihui Foo is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Immune system & Genome-wide association study. The author has an hindex of 9, co-authored 12 publications. Previous affiliations of Shihui Foo include Singapore Immunology Network.
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Papers
Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Svetoslav Chakarov,Hwee Ying Lim,Leonard Tan,Sheau Yng Lim,Peter See,Josephine Lum,Xiao Meng Zhang,Shihui Foo,Satoshi Nakamizo,Kaibo Duan,Wan Ting Kong,Rebecca Gentek,Akhila Balachander,Daniel Carbajo,Camille Bleriot,Benoit Malleret,Benoit Malleret,John Kit Chung Tam,Sonia Baig,Muhammad Shabeer,Sue-Anne Ee Shiow Toh,Andreas Schlitzer,Anis Larbi,Thomas Marichal,Bernard Malissen,Jinmiao Chen,Michael Poidinger,Kenji Kabashima,Kenji Kabashima,Marc Bajénoff,Lai Guan Ng,Veronique Angeli,Florent Ginhoux +32 more
TL;DR: In this article, two independent resident tissue macrophages (RTMs) populations are identified across tissues with specific niche-dependent phenotype and functional programming, and they are slowly replaced by Ly6Chi monocytes.
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Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions.
Maximilien Evrard,Immanuel Kwok,Immanuel Kwok,Shu Zhen Chong,Karen Wei Weng Teng,Etienne Becht,Jinmiao Chen,Je Lin Sieow,Hweixian Leong Penny,Goh Chi Ching,Sapna Devi,José M. Adrover,Jackson LiangYao Li,Jackson LiangYao Li,Ka Hang Liong,Leonard Tan,Zhiyong Poon,Shihui Foo,Jia Wang Chua,I-hsin Su,Karl Balabanian,Françoise Bachelerie,Subhra K. Biswas,Anis Larbi,William Hwang,Vikas Madan,H. Phillip Koeffler,H. Phillip Koeffler,Siew Cheng Wong,Evan W. Newell,Andrés Hidalgo,Andrés Hidalgo,Florent Ginhoux,Lai Guan Ng,Lai Guan Ng +34 more
TL;DR: A workflow of characterizing bone marrow neutrophil subsets on the basis of their proliferative capacity and molecular signatures is demonstrated and thereby define the developmental trajectory and functional properties of neutrophils.
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The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma.
Irene Soncin,Jianpeng Sheng,Qi Chen,Shihui Foo,Kaibo Duan,Josephine Lum,Michael Poidinger,Francesca Zolezzi,Klaus Karjalainen,Christiane Ruedl +9 more
TL;DR: It is shown that in the colon these macrophages are CCR2-dependent, while in tumours they gain the ability to self-renew, relying on CSF1 and promoting cancer progression.
A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
Dilip Kumar,Kia Joo Puan,Anand Kumar Andiappan,Bernett Lee,Geertje H. A. Westerlaken,Doreen Haase,Rossella Melchiotti,Zhuang Li,Nurhashikin Yusof,Josephine Lum,Geraldine Koh,Shihui Foo,Joe Yeong,Joe Yeong,Alexessander Couto Alves,Juha Pekkanen,Liangdan Sun,Astrid Irwanto,Benjamin P. Fairfax,Benjamin P. Fairfax,Vivek Naranbhai,Vivek Naranbhai,John E.A. Common,Mark B Y Tang,Chin Keh Chuang,Chin Keh Chuang,Marjo-Riitta Järvelin,Julian C. Knight,Xuejun Zhang,Fook Tim Chew,Shyam Prabhakar,Liu Jianjun,De Yun Wang,Francesca Zolezzi,Michael Poidinger,E. Birgitte Lane,Linde Meyaard,Olaf Rötzschke +37 more
TL;DR: Low expression of SIRL-1 on monocytes is associated with an increased risk for the manifestation of an inflammatory skin disease and underlines the role of both the cell subset and this inhibitory immune receptor in maintaining immune homeostasis in the skin.
Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection.
Siew-Wai Fong,Nicholas Kim-Wah Yeo,Yi-Hao Chan,Yun Shan Goh,Siti Naqiah Amrun,Nicholas Ang,Menaka Priyadharsani Rajapakse,Josephine Lum,Shihui Foo,Cheryl Yi-Pin Lee,Guillaume Carissimo,Rhonda Sin-Ling Chee,Anthony Torres-Ruesta,Anthony Torres-Ruesta,Matthew Zirui Tay,Zi Wei Chang,Chek Meng Poh,Barnaby Edward Young,Barnaby Edward Young,Paul A. Tambyah,Shirin Kalimuddin,Shirin Kalimuddin,Yee Sin Leo,David C. Lye,Bernett Lee,Subhra K. Biswas,Shanshan W. Howland,Laurent Rénia,Lisa F. P. Ng +28 more
TL;DR: In this paper, RNA-sequencing was performed to elucidate whole blood transcriptomic profiles and identify contrasting immune signatures between patients infected with either wildtype or Δ382 SARS-CoV-2 variant.