Shiho Ohno
Kagawa University
21 Papers
11 Citations
Shiho Ohno is an academic researcher from Kagawa University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 1, co-authored 1 publications.
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Papers
•Journal Article
Induction of nitric oxide production in RAW264.7 cells under serum-free conditions by O-antigen polysaccharide of lipopolysaccharide.
Takeshi Kadowaki,Shiho Ohno,Yoshie Taniguchi,Yoshie Taniguchi,Hiroyuki Inagawa,Chie Kohchi,Gen-Ichiro Soma,Gen-Ichiro Soma +7 more
TL;DR: The present study indicates that the reactivity of LPSp is affected by the O-antigen polysaccharide under serum-free conditions.
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Functional validation of novel variants in B4GALNT1 associated with early‐onset complex hereditary spastic paraplegia with impaired ganglioside synthesis
Julian E. Alecu,Yuhsuke Ohmi,Robiul H. Bhuiyan,Kei-ichiro Inamori,Takahiro Nitta,Afshin Saffari,Hellen Jumo,Marvin Ziegler,Claudio M. de Gusmao,Nutan Sharma,Shiho Ohno,Noriyoshi Manabe,Yoshiki Yamaguchi,Mariko Kambe,Keiko Furukawa,Mustafa Sahin,Jin-ichi Inokuchi,Koichi Furakawa,Darius Ebrahimi-Fakhari +18 more
TL;DR: The case of a 13‐year‐old female who presented with global developmental delay and later mild intellectual disability, progressive spastic diplegia, spastic‐ataxic gait, dysarthria, urinary urgency, and loss of deep tendon reflexes of the lower extremities is illustrated to illustrate the importance of careful phenotyping and functional characterization of novel gene variants.
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O-Glycan-Dependent Interaction between MUC1 Glycopeptide and MY.1E12 Antibody by NMR, Molecular Dynamics and Docking Simulations
Ryoka Kokubu,Shiho Ohno,Hirohide Kuratani,Yuka Takahashi,Noriyoshi Manabe,S. Shimizu,Yasunori Chiba,Kaori Denda-Nagai,Makoto Tsuiji,Tatsuro Irimura,Yoshiki Yamaguchi +10 more
TL;DR: The VH/VL-shared recognition mode of this antibody may be used as a template for the rational design and development of anti-glycopeptide antibodies.
Each N-glycan on human IgA and J-chain uniquely affects oligomericity and stability
Shunli Pan,Shiho Ohno,Sachiko Komatsu,Tsutomu Fujimura,Yoshiki Yamaguchi +4 more
TL;DR: It is concluded that the N459-glycan of IgA1-Fc is essential for dimer formation and prevention of higher-order aggregates while those at N263 (Fc) and N49 (J-chain) stabilize the Fc-J-chain complex.
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Synthesis of the matriglycan hexasaccharide, -3Xylα1-3GlcAβ1-trimer and its interaction with laminin.
Takahiro Tamura,Yuka Omura,Kota Kotera,Ryota Ito,Shiho Ohno,Noriyoshi Manabe,Yoshiki Yamaguchi,Jun-ichi Tamura +7 more
TL;DR: The synthesis of matriglycan-repeating hexasaccharides equipped with an alkyne linker to form glycoconjugates is reported, indicating that a chemical approach may be applied to the reconstruction of muscle tissue.
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