Shigeyuki Yokoyama
University of Tokyo
1125 Papers
10.8K Citations
Shigeyuki Yokoyama is an academic researcher from University of Tokyo. The author has contributed to research in topics: Transfer RNA & Thermus thermophilus. The author has an hindex of 107, co-authored 1113 publications. Previous affiliations of Shigeyuki Yokoyama include University of Tsukuba & RIKEN Brain Science Institute.
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Papers
Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.
Maritza Lienlaf,Fumiaki Hayashi,Francesca Di Nunzio,Naoya Tochio,Takanori Kigawa,Shigeyuki Yokoyama,Felipe Diaz-Griffero +6 more
TL;DR: A role for TRIM5α self-ubiquitylation in the ability of TRIM7α to restrict HIV-1 is demonstrated and several residues, particularly the ones on the E2-binding region of the RING domain, were defective in their self-ubsiclation ability.
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Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
Kazuhiko Yamasaki,Takanori Kigawa,Makoto Inoue,Tomoko Yamasaki,Takashi Yabuki,Masaaki Aoki,Eiko Seki,Takayoshi Matsuda,Yasuko Tomo,Takaho Terada,Mikako Shirouzu,Akiko Tanaka,Motoaki Seki,Kazuo Shinozaki,Shigeyuki Yokoyama +14 more
TL;DR: The major DBD of an EIN3/EIL protein, Arabidopsis thaliana EIL3, containing a key mutational site for DNA binding and signaling (ein3-3 site) is identified, and its solution structure is determined by NMR spectroscopy.
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P-405 site-specific functionalization of proteins by organopalladium reactions
Koichiro Kodama,Seketsu Fukuzawa,Hiroshi Nakayama,Kensaku Sakamoto,Takanori Kigawa,Takashi Yabuki,Natsuko Matsuda,Mikako Shirouzu,Koji Takio,Shigeyuki Yokoyama,Kazuo Tachibana +10 more
- 23 Jul 2006
TL;DR: A new carbon–carbon bond has been regioselectively introduced into a target position (position 32 or 174) of the Ras protein by two types of organopalladium reactions (Mizoroki–Heck and Sonogashira reactions).
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Activation of the Pyrrolysine Suppressor tRNA Requires Formation of a Ternary Complex with Class I and Class II Lysyl-tRNA Synthetases.
Carla Polycarpo,Alexandre Ambrogelly,Benfang Ruan,Debra Tumbula-Hansen,Sandro F. Ataide,Ryuichiro Ishitani,Shigeyuki Yokoyama,Osamu Nureki,Michael Ibba,Dieter Söll +9 more
TL;DR: It is shown that tRNAPyl is efficiently aminoacylated in the presence of both the class I LysRS and class II LysRS of M. barkeri, but not by either enzyme acting alone or by PylS.
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Reassignment of a rare sense codon to a non-canonical amino acid in Escherichia coli.
Takahito Mukai,Atsushi Yamaguchi,Kazumasa Ohtake,Mihoko Takahashi,Akiko Hayashi,Fumie Iraha,Satoshi Kira,Tatsuo Yanagisawa,Shigeyuki Yokoyama,Hiroko Hoshi,Takatsugu Kobayashi,Kensaku Sakamoto +11 more
TL;DR: The in vivo reassignment of the AGG sense codon from arginine to l-homoarginine showed the feasibility of breaking the degeneracy of sense codons to enhance the amino-acid diversity in the genetic code.
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