Shigeru Yagi
Dokkyo University
72 Papers
760 Citations
Shigeru Yagi is an academic researcher from Dokkyo University. The author has contributed to research in topics: Blood pressure & Kidney. The author has an hindex of 17, co-authored 72 publications.
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Papers
Benidipine stimulates nitric oxide synthase and improves coronary circulation in hypertensive rats
Naohiko Kobayashi,Kiminari Kobayashi,Kazuyoshi Hara,Teruo Higashi,Hatsuko Yanaka,Shigeru Yagi,Hiroaki Matsuoka +6 more
TL;DR: It is suggested that benidipine therapy may increase nitrite production and eNOS mRNA expression not only by lessening the endothelial damage by the reduction of blood pressure levels, but also by the stimulation of NOS activity and e NOS mRNA, and this increased N OS activity and ENOS RNA expression may play a role in the amelioration of coronary flow reserve and microvascular remodeling.
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Hydralazine and plasma renin activity.
TL;DR: The findings suggest that the hydralazine test might be useful in the differential diagnosis of hypertension, however, the drug should be used carefully because of untoward side effects.
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Antihypertensive effects of cicletanine and renal protection in Dahl salt-sensitive rats.
Yoshio Uehara,Atsushi Numabe,Nobuhito Hirawa,Yukari Kawabata,Junichi Iwai,Hidehiko Ono,Hiroaki Matsuoka,Yutaka Takabatake,Shigeru Yagi,Tsuneaki Sugimoto +9 more
TL;DR: Data indicate that cicletanine ameliorates the development of hypertension in Dahl-S rats and protects the cardiovascular and renal systems against the injuries seen in the hypertension.
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Genetic predisposition to hypertension facilitates blood pressure elevation in hemodialysis patients treated with erythropoietin
TL;DR: It appears that hemodialysis patients with a positive family history of hypertension are susceptible to developing hypertension during treatment with rHuEPO.
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Effects of intra-atrial injection of colored microspheres on systemic hemodynamics and regional blood flow in rats.
TL;DR: The limits of CMS that can be injected into the rat without inducing hemodynamic changes are established and it is suggested that the CMS technique can be employed to evaluate cardiac output and regional blood flow precisely and repeatedly.
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