Shigeo Mori
Kansai Medical University
20 Papers
321 Citations
Shigeo Mori is an academic researcher from Kansai Medical University. The author has contributed to research in topics: Phosphorylation & Carcinogenesis. The author has an hindex of 8, co-authored 20 publications.
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Papers
TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions.
Shigeo Mori,Koichi Matsuzaki,Katsunori Yoshida,Fukiko Furukawa,Yoshiya Tahashi,Hideo Yamagata,Go Sekimoto,Toshihito Seki,Hirofumi Matsui,Mikio Nishizawa,Jun-ichi Fujisawa,Kazuichi Okazaki +11 more
TL;DR: It is shown that either HGF or TGF-β treatment of normal stomach-origin cells activated the JNK pathway, thereafter inducing endogenous R-Smads phosphorylated at linker regions, which were the common phosphorylation sites for HGF and T GF-β signaling pathways.
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Transforming growth factor-β and platelet-derived growth factor signal via c-jun N-terminal kinase- dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury
Katsunori Yoshida,Koichi Matsuzaki,Shigeo Mori,Yoshiya Tahashi,Hideo Yamagata,Fukiko Furukawa,Toshihito Seki,Mikio Nishizawa,Jun-ichi Fujisawa,Kazuichi Okazaki +9 more
TL;DR: TGF-β and PDGF activate HSCs by transmitting their signals through JNK-mediated Smad2/3 phosphorylation at linker regions, both in vivo and in vitro.
•Journal Article
Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.
Hideo Yamagata,Koichi Matsuzaki,Shigeo Mori,Katsunori Yoshida,Yoshiya Tahashi,Fukiko Furukawa,Go Sekimoto,Toshihiko Watanabe,Yoshiko Uemura,Noriko Sakaida,Kazuhiko Yoshioka,Yasuo Kamiyama,Toshihito Seki,Kazuichi Okazaki +13 more
TL;DR: In this paper, the linker regions of Smad2 and Smad3 were phosphorylated in 31 sporadic colorectal adenocarcinomas, and the extent of phosphorylation in 11 adenomas was intermediate between those in normal epithelial cells and adenocycinomas.
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Sclerosing Esophagitis with IgG4-positive Plasma Cell Infiltration.
Shigeo Mori,Yoshiya Tahashi,Kazushige Uchida,Tsukasa Ikeura,Naoyuki Danbara,Takahiro Wakamatsu,Takeo Kusuda,Yu Takahashi,Masato Yanagawa,Mitsunobu Matsushita,Chisato Ohe,Taku Michiura,Kentaro Inoue,Masanori Kon,Kazuichi Okazaki +14 more
TL;DR: The patient was a 76-year-old woman who had noticed slight difficulty in swallowing in the 3 years prior to this presentation, but her dysphagia progressed while she was hospitalized following cervical cancer surgery, and she was diagnosed with probable IgG4-related disease.
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