Sheng Pan
University of Washington
54 Papers
462 Citations
Sheng Pan is an academic researcher from University of Washington. The author has contributed to research in topics: Pancreatic cancer & Proteomics. The author has an hindex of 35, co-authored 49 publications. Previous affiliations of Sheng Pan include Institute for Systems Biology & Cleveland Clinic.
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Papers
Mass spectrometry based glycoproteomics - from a proteomics perspective
TL;DR: An overview of the recent advances in mass spectrometry based glycoproteomic methods and technology, in the context of biomarker discovery and clinical application is provided.
282
Quantitative Proteomics Analysis Reveals That Proteins Differentially Expressed in Chronic Pancreatitis Are Also Frequently Involved in Pancreatic Cancer
Ru Chen,Teresa A. Brentnall,Sheng Pan,Kelly Cooke,Kara White Moyes,Zhaoli Lane,David A. Crispin,David R. Goodlett,Ruedi Aebersold,Mary P. Bronner +9 more
TL;DR: This study used ICAT technology and tandem mass spectrometry-based proteomics to systematically study protein expression in chronic pancreatitis and validated that cathepsin D, integrin β1, and plasminogen were overexpressed in both pancreatic cancer and chronic pancitis.
157
Proteomic Profiling of Pancreatic Cancer for Biomarker Discovery
TL;DR: Recent progress and challenges for applying quantitative proteomics technologies for biomarker discovery in pancreatic cancer are discussed.
157
Protein alterations associated with pancreatic cancer and chronic pancreatitis found in human plasma using global quantitative proteomics profiling.
Sheng Pan,Ru Chen,David A. Crispin,Damon May,Tyler Stevens,Martin W. McIntosh,Mary P. Bronner,Argyrios Ziogas,Hoda Anton-Culver,Teresa A. Brentnall +9 more
TL;DR: The protein candidates identified in this study provide a biomarker candidate pool for future investigations and may benefit the development of plasma proteomics technology in general.
Pathological implication of protein post-translational modifications in cancer.
Sheng Pan,Ru-Hong Chen +1 more
TL;DR: Protein post-translational modifications (PTMs) profoundly influence protein functions and play crucial roles in essentially all cell biological processes as discussed by the authors , and their crosstalk is linked to many critical signaling events involved in neoplastic transformation, carcinogenesis and metastasis.
108