Sheetal Ramani
Tezpur University
2 Papers
Sheetal Ramani is an academic researcher from Tezpur University. The author has contributed to research in topics: Chemistry & In vivo. The author has an hindex of 2, co-authored 2 publications.
Chat about Author
Papers
Characterization of active anticoagulant fraction and a fibrin(ogen)olytic serine protease from leaves of Clerodendrum colebrookianum, a traditional ethno-medicinal plant used to reduce hypertension.
TL;DR: The potent in vivo anticoagulant and antithrombotic effects of AAFCC suggests its pharmacological significance as herbal anticoAGulant drug for the prevention and/or treatment of hyperfibrinogenemia- and thrombosis associated cardiovascular disorders.
29
The N-terminal-truncated recombinant fibrin(ogen)olytic serine protease improves its functional property, demonstrates in vivo anticoagulant and plasma defibrinogenation activity as well as pre-clinical safety in rodent model.
Bandana Bora,Debananda Gogoi,Debabrata Tripathy,Sillarine Kurkalang,Sheetal Ramani,Anupam Chatterjee,Ashis K. Mukherjee +6 more
TL;DR: It is proposed that [Bacifrinase (ΔN24], at a dose of 2mg/kg, may serve as prototype for the development of potent drug to prevent hyperfibrinogenemia related disorders.
10