Sharon X. Xie
University of Pennsylvania
233 Papers
1.1K Citations
Sharon X. Xie is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 66, co-authored 211 publications. Previous affiliations of Sharon X. Xie include Pennsylvania State University & Leonard Davis Institute of Health Economics.
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Papers
Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease
Staci Hoops,Sarra Nazem,Andrew Siderowf,John E. Duda,Sharon X. Xie,M.B. Stern,Daniel Weintraub +6 more
TL;DR: The Montreal Cognitive Assessment has adequate psychometric properties as a screening instrument for the detection of mild cognitive impairment or dementia in Parkinson disease, however, a positive screen using either instrument requires additional assessment due to suboptimal specificity at the recommended screening cutoff point.
Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial.
Gregory K. Brown,Thomas R. Ten Have,Gregg Henriques,Sharon X. Xie,Judd E. Hollander,Aaron T. Beck +5 more
TL;DR: Cognitive therapy was effective in preventing suicide attempts for adults who recently attempted suicide and reported significantly less hopelessness than the usual care group at 6 months and 18 months.
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Cognitive Therapy for the Prevention of Suicide Attempts
Gregory K. Brown,Gregg Henriques,Sharon X. Xie,Judd E. Hollander,Aaron T. Beck +4 more
- 01 Jan 2005
TL;DR: In this article, the authors evaluated the effectiveness of a 10-session cognitive therapy inter-vention designed to prevent repeated suicide attempts in a randomized controlled trial of 120 individuals who attempted suicide and were evaluated at a hospital emergency department within 48 hours of the attempt.
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre
Jon B. Toledo,Steven E. Arnold,Kevin M. Raible,Johannes Brettschneider,Sharon X. Xie,Murray Grossman,Sarah E. Monsell,Walter A. Kukull,John Q. Trojanowski +8 more
TL;DR: Concurrent cerebrovascular disease is a common neuropathological finding in aged subjects with dementia, is more common in Alzheimer's disease than in other neurodegenerative disorders, especially in younger subjects, and lowers the threshold for dementia due to Alzheimer’s disease and α-synucleinopathies, which suggests that these disorders should be targeted by treatments for cerebroVascular disease.
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Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
John L. Robinson,Edward B. Lee,Sharon X. Xie,Lior Rennert,EunRan Suh,Colin Bredenberg,Carrie Caswell,Vivianna M. Van Deerlin,Ning Yan,Ahmed Yousef,Howard I. Hurtig,Andrew Siderowf,Murray Grossman,Corey T. McMillan,Bruce L. Miller,John E. Duda,John E. Duda,David J. Irwin,David A. Wolk,Lauren Elman,Leo McCluskey,Alice Chen-Plotkin,Daniel Weintraub,Steven E. Arnold,Johannes Brettschneider,Virginia M.-Y. Lee,John Q. Trojanowski +26 more
TL;DR: The data imply that increased age and APOE ɛ4 status are risk factors for co-pathologies independent of neurodegenerative disease; that neurodegenersative disease severity influences co- Pathology as evidenced by the prevalence of co- pathology in high Alzheimer's disease and neocortical Lewy body disease, but not intermediate Alzheimer’s disease or limbic LewyBody disease.
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