Shaowen Wang
Chinese Academy of Sciences
22 Papers
40 Citations
Shaowen Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Grouper & Iridovirus. The author has an hindex of 7, co-authored 10 publications.
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Papers
Entry of a Novel Marine DNA Virus, Singapore Grouper Iridovirus, into Host Cells Occurs via Clathrin-Mediated Endocytosis and Macropinocytosis in a pH-Dependent Manner
Shaowen Wang,Xiaohong Huang,Youhua Huang,Xian Hao,Haijiao Xu,Mingjun Cai,Hongda Wang,Qiwei Qin +7 more
TL;DR: It is demonstrated for the first time that not only the clathrin-dependent pathway but also macropinocytosis are involved in fish DNA enveloped virus entry, thus providing a convenient tactic for exploring the life cycle of DNA viruses.
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Characterization of an envelope gene VP19 from Singapore grouper iridovirus
TL;DR: The current data suggested that VP19 represented a conserved envelope protein in iridovirus, and might contribute greatly to virus assembly during virus infection.
Negative regulation of the antiviral response by grouper LGP2 against fish viruses.
TL;DR: Cloned a LGP2 gene from orange-spotted grouper (EcLGP2) is cloned and its roles in response to grouper virus infection are investigated, suggesting that the negative feedback of interferon immune response by EcL GP2 might contribute to the enhancement of RGNNV infection.
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Real-time Imaging of Rabies Virus Entry into Living Vero cells
Haijiao Xu,Xian Hao,Shaowen Wang,Zhi-Yong Wang,Mingjun Cai,Junguang Jiang,Qiwei Qin,Maolin Zhang,Hongda Wang +8 more
TL;DR: A powerful single-virus tracking technique is utilized to dynamically and globally visualize the infection process of the live attenuated rabies vaccine strain-SRV9 in living Vero cells, finding that the actin-enriched filopodia is in favor of virus reaching to the cell body.
Ultrafast tracking of a single live virion during the invagination of a cell membrane
Yangang Pan,Shaowen Wang,Yuping Shan,Yuping Shan,Dinglin Zhang,Jing Gao,Min Zhang,Shuheng Liu,Mingjun Cai,Haijiao Xu,Guohui Li,Qiwei Qin,Hongda Wang +12 more
TL;DR: High temporospatial resolution (subnanometer and microsecond levels) approaches provides new insight into the dynamic process of viral infection via endocytosis and the mechanism of membrane invagination at the single-particle level.
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