Shaohua Gou
Southeast University
168 Papers
572 Citations
Shaohua Gou is an academic researcher from Southeast University. The author has contributed to research in topics: Chemistry & Cisplatin. The author has an hindex of 25, co-authored 151 publications.
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Papers
Four chiral Ag(I) complexes with dual chiral components: Effect of positional isomerism, luminescence and SHG response
TL;DR: In this article, four chiral Ag(I) complexes with dual chiral components have been synthesized by using a series of (1R,2R)-N1,N2-bis(pyridinylmethyl)cyclohexane-1,2-diamine ligands with different N-positions of pyridyl rings.
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Study on the cytotoxic activity of platinum(II) complexes of (1 R ,2 R )- N 1 -cyclopentyl-1,2-cyclohexanediamine with substituted malonate derivatives
TL;DR: Mechanism studies of cell proliferation inhibition and cellular uptake indicated that complex 2 entered HepG2 cell more efficiently than cisplatin, exhibited massive G2 accumulation and then induced apoptosis, and among the complexes, complex 2 demonstrated the strongest cytotoxic activity.
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Two new nickel(II) complexes constructed by biphenyl-2,2′,6,6′-tetracarboxylic acid: A case study with 2,2′-bipyridine and 1H,1’H-2,2′-biimidazole
Lin Cheng,Fei Liu,Shaohua Gou +2 more
TL;DR: In this article, Ni(II) ions with different terminal ligands (2,2′-bipy and H2biim) in H2O led to the formation of two complexes.
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Three-dimensional hybrid organic-inorganic frameworks based on lanthanide(III) sulfate layers and organic pillars of 1,4-piperazinediacetic acid
Lin Cheng,Shaohua Gou,Gang Xu +2 more
TL;DR: Two types of three-dimensional hybrid organic-inorganic frameworks have been obtained by the reactions of H2pda, lanthanide oxides and H2SO4 under similar hydrothermal conditions as discussed by the authors.
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Hybrid of DNA-targeting Chlorambucil with Pt(IV) Species to Reverse Drug Resistance.
TL;DR: In nude mice with A549/CDDP xenografts, compound 5 exhibited higher anticancer efficacy than cisplatin and chlorambucil by reversing drug resistance, displayed improved effectiveness, and had no toxicity effects.
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