Shaobo Zhou
University of Bedfordshire
72 Papers
201 Citations
Shaobo Zhou is an academic researcher from University of Bedfordshire. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 18, co-authored 49 publications. Previous affiliations of Shaobo Zhou include Jiamusi University & Aberystwyth University.
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Papers
Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease.
Penelope J. Hallett,Anthone W. Dunah,Paula Ravenscroft,Shaobo Zhou,Erwan Bezard,Alan R. Crossman,Jonathan M. Brotchie,David G. Standaert +7 more
TL;DR: It is demonstrated that altered synaptic abundance of NMDA receptors with relative enhancement in the abundance ofNR2A occurs in primate as well as rodent models of parkinsonism, and that in the macaque model, NR2A subunit abundance is further increased in dyskinesia.
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Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice
TL;DR: It is demonstrated that pharmacologic suppression of NLRP3 inflammasome activation controls neuroinflammation, attenuates mitochondrial dysfunction, alleviates the severity of spinal cord damage, and improves neurological recovery after SCI.
Striatal histone modifications in models of levodopa-induced dyskinesia
Anthony P. Nicholas,Anthony P. Nicholas,Farah D. Lubin,Penelope J. Hallett,Padmapriya Vattem,Paula Ravenscroft,Erwan Bezard,Shaobo Zhou,Susan H. Fox,Jonathan M. Brotchie,J. David Sweatt,David G. Standaert +11 more
TL;DR: Stark changes in striatal histones associated with the induction of LDID in both animal models are demonstrated, suggesting that inhibitors of H4 deacetylation may be useful in preventing or reversing LDID.
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Downregulation of hsa_circ_0000285 serves as a prognostic biomarker for bladder cancer and is involved in cisplatin resistance.
Bao-Jin Chi,D.M. Zhao,L Liu,X Z Yin,Fang-Fang Wang,Sheng Bi,Shi-Liang Gui,Shaobo Zhou,Shaobo Zhou,Wen-Bo Qin,D M Wu,Shu-Qiu Wang +11 more
TL;DR: This study indicates hsa_circ_0000285 may be a novel biomarker for bladder cancer because of its involvement in bladder cancer chemo-sensitivity.
Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer
Jianjie Wang,Jianjie Wang,Qingwang Li,Qingwang Li,Yetao Ou,Yetao Ou,Zengsheng Han,Kun Li,Peijun Wang,Peijun Wang,Shaobo Zhou +10 more
TL;DR: It is concluded that ad-rhLTF inhibits tumor growth by inducing tumor cell apoptosis in mice with breast cancer by triggering the mitochondrial-dependent pathway and activation of caspase 3.
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