Shanshan Li
Peking Union Medical College
12 Papers
10 Citations
Shanshan Li is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Stem cell & Medicine. The author has an hindex of 5, co-authored 7 publications.
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Papers
MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1
Shilin Yang,Yexiong Li,Jing Gao,Taiping Zhang,Shanshan Li,Aiping Luo,Huilin Chen,Fang Ding,Xiuqin Wang,Zhihua Liu +9 more
TL;DR: It is demonstrated that miR-34a/c functions as a metastasis suppressor to regulate breast cancer migration and invasion through targeting Fra-1 oncogene and suggested a therapeutic application of mi R-34 in breast cancer.
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Acidosis enhances the self-renewal and mitochondrial respiration of stem cell-like glioma cells through CYP24A1-mediated reduction of vitamin D
Peishan Hu,Shanshan Li,Ningyu Tian,Fan Wu,Yan Hu,Dengke Li,Yingjiao Qi,Zhizhong Wei,Qunfang Wei,Yanchao Li,Bin Yin,Tao Jiang,Jiangang Yuan,Boqin Qiang,Wei Han,Xiaozhong Peng +15 more
TL;DR: This study indicates that the acidosis–CYP24A1–vitamin D pathway may be a key regulator of the cancer stem cell phenotype in malignant glioma and point out the potential value for the utilization of vitamin D to target cancer stem cells and to restrain the growth of malignantglioma in the future.
NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma
Peishan Hu,Xia Qs,Fan Wu,Dengke Li,Yingjiao Qi,Ying Hu,Zhizhong Wei,Shanshan Li,Ningyu Tian,Qunfang Wei,Shen Lj,Bin Yin,Tao Jiang,Jupeng Yuan,Boqin Qiang,Wei Han,Peng Xz +16 more
TL;DR: The results demonstrate that NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of ATRA via targeting RDH16 and may provide novel targets for glioma treatment in the future.
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Amphibian-derived peptide homodimer OA-GL17d promotes skin wound regeneration through the miR-663a/TGF-β1/Smad axis
Yue Zhang,Yingli Wang,Lin Zeng,Yixiang Liu,Huiling Sun,Shanshan Li,Siyu Wang,Longjun Shu,Naixin Liu,Saige Yin,Junsong Wang,Dan Ni,Yutong Wu,Ying Yang,Li He,Buliang Meng,Xinwang Yang +16 more
TL;DR: This study emphasizes the importance of exogenous peptides as molecular probes for exploring competing endogenous RNA mechanisms and indicates that miR-663a may be an effective target for promoting skin repair.
Glioma-associated human endothelial cell-derived extracellular vesicles specifically promote the tumourigenicity of glioma stem cells via CD9.
Dengke Li,Yuan Tian,Yan Hu,Yingjiao Qi,Ningyu Tian,Shanshan Li,Peishan Hu,Fan Wu,Qunfang Wei,Zhizhong Wei,Shanshan Wang,Bin Yin,Tao Jiang,Jiangang Yuan,Boqin Qiang,Wei Han,Xiaozhong Peng +16 more
TL;DR: It is shown that glioma-associated human endothelial cells (GhECs), a main component of the perivascular niche, release extracellular vesicles (EVs) that increase GSC proliferation and tumour-sphere formation and enhances the aggressiveness of glioblastoma by specifically maintaining GSCs.
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