Shane Thomas
QIMR Berghofer Medical Research Institute
6 Papers
101 Citations
Shane Thomas is an academic researcher from QIMR Berghofer Medical Research Institute. The author has contributed to research in topics: Single-nucleotide polymorphism & Endometriosis. The author has an hindex of 5, co-authored 6 publications.
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Papers
Common sequence variants on 20q11.22 confer melanoma susceptibility
Kevin M. Brown,Stuart MacGregor,Grant W. Montgomery,David Craig,Zhen Zhen Zhao,Kelly Iyadurai,Anjali K. Henders,Nils Homer,Megan Campbell,Mitchell S. Stark,Shane Thomas,Helen Schmid,Elizabeth A. Holland,Elizabeth M. Gillanders,David L. Duffy,Judith A. Maskiell,Jodie Jetann,Megan Ferguson,Dietrich A. Stephan,Anne E. Cust,David C. Whiteman,Adèle C. Green,Håkan Olsson,Susana Puig,Paola Ghiorzo,Johan Hansson,Florence Demenais,Alisa M. Goldstein,Nelleke A. Gruis,David E. Elder,Julia A. Newton Bishop,Richard F. Kefford,Graham G. Giles,Bruce K. Armstrong,Joanne F. Aitken,John L. Hopper,Nicholas G. Martin,Jeffrey M. Trent,Graham J. Mann,Nicholas K. Hayward +39 more
TL;DR: A new melanoma risk locus on chromosome 20 is identified using pooling and replication in samples totaling 2,019 cases and 2,105 controls, with evidence for stronger association in early-onset cases.
Polymorphisms in the vascular endothelial growth factor gene and the risk of familial endometriosis.
TL;DR: A detailed review and meta-analysis of the V EGF polymorphisms suggests that genotyping assay problems may underlie the previously reported associations between VEGF variants and endometriosis.
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Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample
Zhen Zhen Zhao,Dale R. Nyholt,Lien Le,Shane Thomas,Christian R. Engwerda,Louise M. Randall,Susan A. Treloar,Grant W. Montgomery +7 more
TL;DR: The data suggest both TNF and LTA genes are not major susceptibility genes for endometriosis, and there was no evidence for association between endometRIosis and TNF/LTA SNPs or SNP haplotypes in the case-control study.
Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.
Zhen Zhen Zhao,Pamela M. Pollock,Shane Thomas,Susan A. Treloar,Dale R. Nyholt,Grant W. Montgomery +5 more
TL;DR: Common variation in the breast-cancer implicated intron 2 and other highly plausible causative candidate regions of FGFR2 do not appear to be a major contributor to endometriosis susceptibility in a large Australian sample.
Polymorphisms in the syntaxin 17 gene are not associated with human cutaneous malignant melanoma.
Zhen Zhen Zhao,David L. Duffy,Shane Thomas,Nicholas G. Martin,Nicholas K. Hayward,Grant W. Montgomery +5 more
TL;DR: It is concluded that common variants in the STX17 gene region do not play a key role in the pathogenesis of human melanoma and provide no evidence for interactions between the melanoma risk SNP rs910873 on chromosome 20 and any of theSTX17 SNPs.
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