Shan Chen
Fuzhou University
22 Papers
127 Citations
Shan Chen is an academic researcher from Fuzhou University. The author has contributed to research in topics: Chemistry & Detection limit. The author has an hindex of 14, co-authored 18 publications. Previous affiliations of Shan Chen include Nanjing University & Shanghai Jiao Tong University.
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Papers
An Ultrasound Activated Vesicle of Janus Au-MnO Nanoparticles for Promoted Tumor Penetration and Sono-Chemodynamic Therapy of Orthotopic Liver Cancer
TL;DR: This smart nanoplatform designed by this work designed ultrasound (US) and glutathione (GSH) dual responsive vesicles of Janus Au-MnO nanoparticles (JNPs) coated with PEG and a ROS-sensitive polymer with great potential in deep tumor diagnosis and therapy.
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Nongenetic Approach for Imaging Protein Dimerization by Aptamer Recognition and Proximity-Induced DNA Assembly.
Hong Liang,Shan Chen,Li Peipei,Liping Wang,Jingying Li,Juan Li,Juan Li,Huanghao Yang,Weihong Tan,Weihong Tan +9 more
TL;DR: This approach allows us to image the two states (monomer/dimer) of a receptor protein on living cell surfaces in real time, opening a universal method for further investigation of protein dimerization and the corresponding activation processes in signal transduction.
118
Ultrasound activation of liposomes for enhanced ultrasound imaging and synergistic gas and sonodynamic cancer therapy
Xiahui Lin,Yuan Qiu,Liang Song,Shan Chen,Xiaofeng Chen,Guoming Huang,Jibin Song,Xiaoyuan Chen,Huanghao Yang +8 more
- 23 Apr 2019
TL;DR: Ultrasound (US) imaging is widely applied in hospital and clinical settings due to its non-invasiveness, controllability, and high tissue-penetrating ability.
107
GSH-Responsive Radiosensitizers with Deep Penetration Ability for Multimodal Imaging-Guided Synergistic Radio-Chemodynamic Cancer Therapy
TL;DR: The combination of JNP Ve and X‐ray irradiation achieves multimodal image‐guided ablation of subcutaneous as well as deep‐seated tumors in murine models, which is a promising strategy in high‐precision tumor therapy.
89
Repeatable deep-tissue activation of persistent luminescent nanoparticles by soft X-ray for high sensitivity long-term in vivo bioimaging.
TL;DR: This work presents a new strategy for the activation of PLNPs (SrAl2O4:Eu2+) by using soft X-ray excitation to bring new insights for deep tissue and long-term bioimaging in living animals, and provide new perspectives for persistent luminescence bioim imaging and therapeutic applications.
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