Séverine Divoux
Centre national de la recherche scientifique
5 Papers
11 Citations
Séverine Divoux is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Endosome & Golgi apparatus. The author has an hindex of 5, co-authored 5 publications. Previous affiliations of Séverine Divoux include PSL Research University & Curie Institute.
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Papers
ESCRT Machinery Is Required for Plasma Membrane Repair
Ana Joaquina Jimenez,Ana Joaquina Jimenez,Paolo Maiuri,Paolo Maiuri,Julie Lafaurie-Janvore,Julie Lafaurie-Janvore,Séverine Divoux,Séverine Divoux,Matthieu Piel,Matthieu Piel,Franck Perez,Franck Perez +11 more
TL;DR: The results show that ESCRT proteins play an important role in the detection and removal through the extracellular shedding of small wounds present at the plasma membrane that reseals small wounds caused by toxins or laser treatment.
612
Synchronization of secretory protein traffic in populations of cells
Gaelle Boncompain,Séverine Divoux,Séverine Divoux,Nelly Gareil,Nelly Gareil,Hélène de Forges,Hélène de Forges,Aurianne Lescure,Lynda Latreche,Valentina Mercanti,Valentina Mercanti,Florence Jollivet,Florence Jollivet,Graça Raposo,Graça Raposo,Franck Perez,Franck Perez +16 more
TL;DR: To dissect secretory traffic, the retention using selective hooks (RUSH) system is developed and preliminarily that the RUSH system is usable for automated screening, which should help increase the understanding of the mechanisms of trafficking and enable screens for molecules that perturb pathological protein transport.
558
Fully in vitro selection of recombinant antibodies
TL;DR: A new antibody selection approach where antigens are produced through in vitro translation and are used directly and without the need for purification, which may broaden the use of the recombinant approach for antibody generation.
12
Stiffness tomography of eukaryotic intracellular compartments by atomic force microscopy
Sébastien Janel,Michka Popoff,Michka Popoff,Nicolas Barois,Elisabeth Werkmeister,Séverine Divoux,Franck Perez,Frank Lafont +7 more
TL;DR: The ability of atomic force microscopy to also map and characterize organelles and microorganisms inside cells, at the nanoscale, is demonstrated by combining stiffness tomography with super-resolution fluorescence and electron microscopy.
Microtubule-independent secretion requires functional maturation of Golgi elements.
Lou Fourriere,Lou Fourriere,Lou Fourriere,Séverine Divoux,Séverine Divoux,Mila Roceri,Mila Roceri,Franck Perez,Franck Perez,Gaelle Boncompain,Gaelle Boncompain +10 more
TL;DR: It is demonstrated that functional maturation of Golgi elements is needed to ensure post-Golgi trafficking, and that microtubule-driven post-golgi transport is not strictly required.