Seunghoon Han
Catholic University of Korea
69 Papers
158 Citations
Seunghoon Han is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Population & NONMEM. The author has an hindex of 11, co-authored 68 publications. Previous affiliations of Seunghoon Han include St Mary's Hospital.
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Papers
A Population Pharmacokinetic–Pharmacodynamic Model for Simvastatin that Predicts Low‐Density Lipoprotein‐Cholesterol Reduction in Patients with Primary Hyperlipidaemia
Jimyon Kim,Byung-Jin Ahn,Hong-Seok Chae,Hong-Seok Chae,Seunghoon Han,Seunghoon Han,Kichan Doh,Kichan Doh,Jeongeun Choi,Yong K. Jun,Yong W. Lee,Dong-Seok Yim,Dong-Seok Yim +12 more
TL;DR: A simple PK-PD model developed using only 2-week study data from fewer than 30 healthy volunteers successfully predicted the dose-response relationship of simvastatin in patients when compared with published data.
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Model-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndrome
Seunghoon Han,Yoo-Jin Kim,Jongtae Lee,Sangil Jeon,Taegon Hong,Gab-jin Park,Jae-Ho Yoon,Seung-Ah Yahng,Seung-Hwan Shin,Sung-Eun Lee,Ki-Seong Eom,Hee-Je Kim,Chang-Ki Min,Seok Lee,Dong-Seok Yim +14 more
TL;DR: It is determined that 5 mg/m2/day is considered to be the most appropriate starting dose for the regimen studied and individualized the maintenance dose for each patient, while minimizing the toxicity using the adaptive approach.
Therapeutic drug monitoring and safety of intravenous voriconazole formulated with sulfobutylether β-cyclodextrin in haematological patients with renal impairment
Si-Hyun Kim,Jae-Cheol Kwon,Chulmin Park,Seunghoon Han,Dong-Seok Yim,Jae-Ki Choi,Sung-Yeon Cho,Hyo-Jin Lee,Sun Hee Park,Su-Mi Choi,Jung-Hyun Choi,Jin-Hong Yoo,Dong-Gun Lee,Jong Wook Lee +13 more
TL;DR: The clinical effects of intravenous voriconazole formulated with sulfobutylether β‐cyclodextrin (SBECD) in patients with renal impairment did not lead to a higher incidence of severe adverse events including nephrotoxicity in haematological patients with CrCl <50 ml min−1.
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Anatomical and radiological study of the superior and inferior gluteal arteries in the gluteus maximus muscle for musculocutaneous flap in Koreans
TL;DR: The position, distribution pattern, and perforating branch of the superior gluteal artery and the inferior glutesal artery in the gluteus maximus muscle (GMM) were investigated through fine dissection and the radiological method.
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A simplified prognostic model to predict mortality in patients with acute variceal bleeding.
Han Hee Lee,Jae Myung Park,Seunghoon Han,Sung Min Park,Hee Yeon Kim,Jung Hwan Oh,Chang Wook Kim,Seung Kew Yoon,Myung-Gyu Choi +8 more
TL;DR: A new simple prognostic model accurately and consistently predicted 6-week mortality in patients with AVB using objective variables measured at admission and can be used to identify high risk AVB patients.
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