Seung-Heon Yoon
Iowa State University
16 Papers
81 Citations
Seung-Heon Yoon is an academic researcher from Iowa State University. The author has contributed to research in topics: Leuconostoc mesenteroides & Acarbose. The author has an hindex of 12, co-authored 16 publications.
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Papers
Dextransucrase and the mechanism for dextran biosynthesis.
TL;DR: It is shown how the three conserved amino acids at the active sites of glucansucrases participate in the polymerization of dextran and related glucans from a single active site by the addition of the D-glucose moiety of sucrose to the reducing-ends of the covalently linked glucan chains in a two catalytic-site, insertion mechanism.
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Study of the inhibition of four alpha amylases by acarbose and its 4IV-α-maltohexaosyl and 4IV-α-maltododecaosyl analogues
Seung-Heon Yoon,John F. Robyt +1 more
TL;DR: The G6-Aca and G12-A Ca analogues are the most potent alpha-amylase inhibitors observed, with Ki values one to three orders of magnitude more potent than acarbose, which itself was one toThree orders of order of magnitudeMore potent than other known alpha-AMylase inhibitor.
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Molecular cloning of a gene encoding the sucrose phosphorylase from Leuconostoc mesenteroides B-1149 and the expression in Escherichia coli
TL;DR: Leuconostoc mesenteroides NRRL B-1149 sucrose phosphorylase (SPase) gene, 1149sp, was isolated and characterized and had a broad range of acceptor specificity and transferred the glucosyl moiety of sucrose or glucose-1-phosphate to various acceptors.
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Synthesis of acarbose analogues by transglycosylation reactions of Leuconostoc mesenteroides B-512FMC and B-742CB dextransucrases.
Seung-Heon Yoon,John F. Robyt +1 more
TL;DR: Two new acarbose analogues were synthesized by the reaction of acarbOSE with sucrose and dextransucrases from Leuconostoc mesenteroides B-512FMC and B-742CB.
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Enzymatic synthesis of two salicin analogues by reaction of salicyl alcohol with Bacillus macerans cyclomaltodextrin glucanyltransferase and Leuconostoc mesenteroides B-742CB dextransucrase.
TL;DR: Two new salicin analogues have been enzymatically synthesized by transglycosylation reactions to give alpha-d-glucopyranose attached to the primary alcohol hydroxyl of salicyl alcohol as the major product, alpha-isosalicin.
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