Sergio Bizzarro
Academic Center for Dentistry Amsterdam
29 Papers
20 Citations
Sergio Bizzarro is an academic researcher from Academic Center for Dentistry Amsterdam. The author has contributed to research in topics: Periodontitis & Medicine. The author has an hindex of 13, co-authored 24 publications. Previous affiliations of Sergio Bizzarro include University of Amsterdam.
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Papers
Subgingival microbiome in smokers and non-smokers in periodontitis: an exploratory study using traditional targeted techniques and a next-generation sequencing
TL;DR: In periodontitis, there is a difference in the composition of the subgingival microbiome between smokers and non-smokers, as revealed by pyrosequencing, which supports the hypothesis of the ecological microbial-host interaction in the severity of periodontal disease.
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Periodontitis is characterized by elevated PAI-1 activity
Sergio Bizzarro,U. van der Velden,J. M. A. G. ten Heggeler,E. Leivadaros,Frans J. Hoek,Victor E. A. Gerdes,Stephan J. L. Bakker,Reinold O. B. Gans,H. ten Cate,Bruno G. Loos +9 more
TL;DR: Elevated levels of PAI-1 activity may increase the potential for impaired fibrinolysis, a condition that results in a prothrombotic state that may contribute to an increased risk for CVD.
81
Colorimetric Assay for the Detection of Typical Biomarkers for Periodontitis Using a Magnetic Nanoparticle Biosensor
Shayalini Wignarajah,Shayalini Wignarajah,Ghadeer A. R. Y. Suaifan,Sergio Bizzarro,Floris J. Bikker,Wendy E. Kaman,Wendy E. Kaman,Mohammed Zourob +7 more
TL;DR: Examination of periodontitis patients' sample and a healthy control showed the potential of the multiplex biosensor to detect the presence of HNE and Cathepsin-G activity in situ, anticipated to be a useful biochip array amenable to low-cost point-of-care devices.
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A rapid, non-invasive tool for periodontitis screening in a medical care setting.
Martijn J. L. Verhulst,Wijnand J. Teeuw,Sergio Bizzarro,Joris Muris,Naichuan Su,Elena A. Nicu,Kamran Nazmi,Floris J. Bikker,Bruno G. Loos +8 more
TL;DR: The prediction models for total and severe periodontitis proved to be feasible and accurate, resulting in easily applicable screening tools, intended for a non-dental setting.
A Lead ANRIL Polymorphism Is Associated with Elevated CRP Levels in Periodontitis: A Pilot Case-Control Study.
TL;DR: This study is the first to show that, in addition to gender and BMI, also a leading SNP in ANRIL is explanatory for inter-individual variation in hsCRP levels in periodontitis patients of North European descent.