Sergey Chirkov
Moscow State University
5 Papers
111 Citations
Sergey Chirkov is an academic researcher from Moscow State University. The author has contributed to research in topics: Tobacco mosaic virus & RNA. The author has an hindex of 4, co-authored 5 publications.
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Papers
Thermal transition of native tobacco mosaic virus and RNA-free viral proteins into spherical nanoparticles.
TL;DR: In this article, spherical nanoparticles (SNPs) were generated by two-step thermal remodelling of native tobacco mosaic virus (TMV) at 94 °C Particles of irregular shape and varying size were converted into SNPs by heating at 94°C and were considered to be intermediate precursors of SNPs In addition, SNP monomers (53 nm diameter), generated by individual TMV virions, were assembled.
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Short Communication Thermal transition of native tobacco mosaic virus and RNA-free viral proteins into spherical nanoparticles
Joseph Atabekov,Nikolai Nikitin,M. V. Arkhipenko,Sergey Chirkov,Olga Karpova +4 more
- 01 Jan 2011
TL;DR: Results show that SNPs represent a new type of particle nanoplatform for producing compositions of SNPs with foreign protein molecules bound to their surface.
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Immunogenic compositions assembled from tobacco mosaic virus-generated spherical particle platforms and foreign antigens.
Olga Karpova,Nikolai Nikitin,Sergey Chirkov,E.A. Trifonova,Anna Sheveleva,Ekaterina A. Lazareva,Joseph Atabekov +6 more
TL;DR: It is shown that SPs represent a universal particle platform that can form compositions by binding a diversity of various foreign proteins/epitopes of viral and non-viral origin to their surface.
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Characterization of Alternanthera mosaic virus and its Coat Protein.
Anna A. Mukhamedzhanova,A. A. Smirnov,M. V. Arkhipenko,Peter Ivanov,Sergey Chirkov,Nina Rodionova,Olga Karpova,Joseph Atabekov +7 more
TL;DR: It has been shown that the AltMV-MU coat protein (CP) can be efficiently reassembled in vitro under different conditions into helical RNA-free virus-like particles (VLPs) antigenically related to native virus.
Patent
Spherical nano- and microparticles derived from plant viruses for the display of foreign proteins or epitopes
Iosif Grigorievich Atabekov,Olga Karpova,Mikhail P. Kirpichnikov,Nikolay Alexandrovich Nikitin,Sergey Chirkov,E.A. Trifonova,Anna Sheveleva,Marina Vladimirovna Archipenko +7 more
- 15 Feb 2011
TL;DR: In this article, a novel type of particle platform for application in biotechnology is provided by the present invention, which comprises RNA-free particles generated by thermal denaturation and structural remodeling of helical plant viruses.
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