Sen Wang
Fudan University
48 Papers
138 Citations
Sen Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 13, co-authored 37 publications.
Chat about Author
Papers
HBsAg inhibits IFN-α production in plasmacytoid dendritic cells through TNF-α and IL-10 induction in monocytes.
TL;DR: It is determined that plasma-derived hepatitis B surface antigen (HBsAg) and HBsAg expressed in CHO cells can significantly inhibit toll like receptor (TLR) 9-mediated Interferon-α (IFN-α) production in peripheral blood mononuclear cells (PBMCs) from healthy donors.
Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells.
Chanyi Lu,Jing Wu,Honghai Wang,Sen Wang,Ni Diao,Feifei Wang,Yan Gao,Jiazhen Chen,Lingyun Shao,Xinhua Weng,Ying Zhang,Ying Zhang,Wenhong Zhang +12 more
TL;DR: A genome-wide transcriptome approach to identify immune factors associated with MTB infection and novel biomarkers that can distinguish active disease from latent infection indicated that a combination of CXCL10, ATP10A and TLR6 could be used as novel biomarker for the discrimination of TB from LTBI.
Geriatric risk and protective factors for serious COVID-19 outcomes among older adults in Shanghai Omicron wave
Guanzhu Lu,Yi Zhang,Haocheng Zhang,Jing-Wen Ai,Liu He,Xiaoling Yuan,Suxia Bao,Xiaohua Chen,Hongyu Wang,Jia Cai,Sen Wang,Wen Zhang,Jie Xu +12 more
TL;DR: It was demonstrated that in the elderly older than 60 years old, older age (aged over 80), cerebrovascular disease, and chronic kidney disease were risk factors for severe infection, and fully vaccination was a significant protective factor against severe infections.
69
An open, prospective cohort study of VV116 in Chinese participants infected with SARS-CoV-2 omicron variants
Yinzhong Shen,Jing-Wen Ai,Na Lin,Haocheng Zhang,Yang Li,Hongyu Wang,Sen Wang,Zhen Ping Wang,Tao Li,Feng Sun,Zhenyu Fan,Liqun Li,Yunfei Lu,Xianmin Meng,Hong Xiao,Huiliang Hu,Yun Ling,Feng Li,Hongdi Li,Chunmei Xi,Liping Gu,Wen Zhang,Xiao-Bo Fan +22 more
TL;DR: V116 is a safe, effective oral antiviral drug, which shows a better performance within the early onset of omicron infection, and is evaluated in Chinese participants infected with SARS-CoV-2 from March 8th, 2022 to March 24th of 2022.
55
Underestimation of the resistance of Mycobacterium tuberculosis to second-line drugs by the new GenoType MTBDRsl test.
TL;DR: It is demonstrated that genotypic resistance to ethambutol, kanamycin, and ofloxacin in MTB can be quickly determined with the MTBDRsl and could function as a supplement to traditional DST.
27