Sen Li
Peking University
6 Papers
3 Citations
Sen Li is an academic researcher from Peking University. The author has contributed to research in topics: Adipogenesis & MAPK/ERK pathway. The author has an hindex of 3, co-authored 4 publications.
Chat about Author
Papers
The protective role of microRNA-21 against coxsackievirus B3 infection through targeting the MAP2K3/P38 MAPK signaling pathway
TL;DR: In this paper, microRNA-21 has potential inhibitory effect on the MAP2K3 which locates upstream of P38 MAPK and was upregulated in mouse hearts upon CVB3 infection.
A time-resolved proteomic analysis of transcription factors regulating adipogenesis of human adipose derived stem cells.
TL;DR: This study identified and verified three TFs (BATF3, MAFF and MXD4) as novel regulators of adipogenesis, whose over-expression could inhibit adipogenesis of hADSCs in vitro, and provided a valuable TFs resource to understand the complex process of adipesis.
11
Vitamin D inhibits palmitate-induced macrophage pro-inflammatory cytokine production by targeting the MAPK pathway
TL;DR: The data suggest that the attenuation of palmitate-induced TNF-α and IL-6 gene expression and protein secretion by vitamin D are associated with reduced activation of JNK and ERK1/2.
10
A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells
TL;DR: The ATAC-seq method was applied to depict a high-quality genome‐wide time-resolved accessible chromatin atlas during adipogenesis of human adipose-derived stem cells (hASCs) and indicated that the chromatin accessibility drastic dynamically reformed during the adipogenic of hASCs and 8 h may be the critical transition node of adipogenesis chromatin states from commitment phase to determination phase.
5
Engineered coxsackievirus B3 containing multiple organ-specific miRNA targets showed attenuated viral tropism and protective immunity.
TL;DR: In this article , an engineered CVB3 harboring three different tissue-specific miRNA targets (CVB3-miR3*T) was constructed to decrease the virulence of the virus in muscles, pancreas, and brain.
4