Seiji Maruo
Hokkaido University
29 Papers
376 Citations
Seiji Maruo is an academic researcher from Hokkaido University. The author has contributed to research in topics: Epstein–Barr virus & Virus. The author has an hindex of 21, co-authored 29 publications.
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Papers
Oncogenic Role of Epstein-Barr Virus-Encoded RNAs in Burkitt’s Lymphoma Cell Line Akata
TL;DR: Transfection of the EBER genes into EBV-negative Akata clones restored the capacity for growth in soft agar, tumorigenicity in SCID mice, resistance to apoptotic inducers, and upregulated expression of bcl-2 oncoprotein.
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Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression
TL;DR: EBNA3C and EBNA3A joint repression of CDKN2A p16INK4A and p14ARF is essential for LCL growth, indicating that EBV conversion of primary human B lymphocytes into continuously proliferating lymphoblast cell lines (LCLs) and for maintaining LCLgrowth are each essential.
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Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes.
TL;DR: It is demonstrated that the Epstein-Barr virus BZLF1 gene, a switch from latent infection to lytic infection, is expressed as early as 1.5 h after EBV infection in Burkitt's lymphoma-derived, EBV-negative Akata and Daudi cells and primary B lymphocytes.
115
RNAs induced by Epstein–Barr virus nuclear antigen 2 in lymphoblastoid cell lines
Bo Zhao,Seiji Maruo,Andrew Cooper,Michael R. Chase,Eric Johannsen,Elliott Kieff,Ellen Cahir-McFarland +6 more
TL;DR: Real-time RT-PCR confirmed EBNA2-dependent expression of eight RNAs important in cell adhesion or signaling, transcription, RNA processing, cell-cycle regulation, and survival in LCLs.
92
Roles of Epstein-Barr virus glycoproteins gp350 and gp25 in the infection of human epithelial cells
TL;DR: Results indicate the existence of two distinct pathways in EBV infection of epithelial cells, agp350-dependent pathway and a gp350-independent pathway, and that gp25 can play a role in the infection of some epithelial Cells.
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