Seigo Terawaki
Osaka City University
6 Papers
2 Citations
Seigo Terawaki is an academic researcher from Osaka City University. The author has contributed to research in topics: Histamine & Innate immune system. The author has an hindex of 3, co-authored 6 publications.
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Papers
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury
Shuhei Nakamura,Saki Shigeyama,Satoshi Minami,Takayuki Shima,Shiori Akayama,Tomoki Matsuda,Alessandra Esposito,Gennaro Napolitano,Akiko Kuma,Tomoko Namba-Hamano,Jun Nakamura,Kenichi Yamamoto,Miwa Sasai,Ayaka Tokumura,Mika Miyamoto,Yukako Oe,Toshiharu Fujita,Seigo Terawaki,Atsushi Takahashi,Maho Hamasaki,Masahiro Yamamoto,Yukinori Okada,Masaaki Komatsu,Takeharu Nagai,Yoshitsugu Takabatake,Haoxing Xu,Yoshitaka Isaka,Andrea Ballabio,Tamotsu Yoshimori +28 more
TL;DR: It is shown that transcription factor EB (TFEB) is activated during the lysosomal damage response, and its activation is dependent on the function of the ATG conjugation system, which mediates LC3 lipidation.
166
Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.
Daisuke Oikawa,Yusuke Sato,Yusuke Sato,Fumiaki Ohtake,Fumiaki Ohtake,Keidai Komakura,Kazuki Hanada,Koji Sugawara,Seigo Terawaki,Yukari Mizukami,Hoang T. Phuong,Kiyosei Iio,Shingo Obika,Masaya Fukushi,Takashi Irie,Daisuke Tsuruta,Shinji Sakamoto,Keiji Tanaka,Yasushi Saeki,Shuya Fukai,Fuminori Tokunaga +20 more
- 03 Apr 2020
TL;DR: HOPINs effectively induce cell death in activated B cell-like diffuse large B cell lymphoma cells, and alleviate imiquimod-induced psoriasis in model mice, suggesting the potential therapeutic utility of HOIPINs.
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Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling
Naruhito Iwasaki,Seigo Terawaki,Kouhei Shimizu,Daisuke Oikawa,Hirokazu Sakamoto,Kishiko Sunami,Fuminori Tokunaga +6 more
TL;DR: In this paper, the authors investigated the relationship between histamine, macrophages, and Th2 cells in allergic inflammation, and established a macrophage-Th2 cell co-culture model in vitro and an antigen-specific Th2 cell transfer mouse model of rhinitis.
RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages
Jan Valečka,Voahirana Camosseto,David G. McEwan,Seigo Terawaki,Zhuangzhuang Liu,Eva Strock,Catarina R. Almeida,Bing Su,Ivan Dikic,Yinming Liang,Evelina Gatti,Philippe Pierre +11 more
TL;DR: In this article, a newly characterized member of the ‘RUN and FYVE domain-containing’ family of proteins was shown to interact with mitochondria upon stimulation by microbial-associated molecular patterns of AM and dendritic cells.
5
Th2 cell-derived histamine is involved in nasal Th2 infiltration in mice.
Naruhito Iwasaki,Seigo Terawaki,Kouhei Shimizu,Daisuke Oikawa,Hirokazu Sakamoto,Kishiko Sunami,Fuminori Tokunaga +6 more
TL;DR: In this article, the role of T helper 2 (Th2) cell-derived histamine in nasal allergic disorders was revealed, and the histamine production from Th2 cells was measured by EIA.
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