Sean Powell
Austrian Academy of Sciences
15 Papers
18 Citations
Sean Powell is an academic researcher from Austrian Academy of Sciences. The author has contributed to research in topics: Biology & Cohesin. The author has an hindex of 11, co-authored 14 publications. Previous affiliations of Sean Powell include Swiss Institute of Bioinformatics & Heidelberg Institute for Theoretical Studies.
Chat about Author
Papers
eggNOG v4.0: nested orthology inference across 3686 organisms
Sean Powell,Kristoffer Forslund,Damian Szklarczyk,Kalliopi Trachana,Alexander Roth,Jaime Huerta-Cepas,Toni Gabaldón,Thomas Rattei,Christopher J. Creevey,Michael Kuhn,Lars Juhl Jensen,Christian von Mering,Peer Bork +12 more
TL;DR: The eggNOG database as mentioned in this paper provides a comprehensive characterization and analysis pipeline to derive nonsupervised orthologous groups (NOGs) from complete genomes, and then applies a comprehensive analysis to the resulting gene families.
623
eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges
Sean Powell,Damian Szklarczyk,Kalliopi Trachana,Alexander Roth,Michael Kuhn,Jean Muller,Roland Arnold,Thomas Rattei,Ivica Letunic,Tobias Doerks,Lars Juhl Jensen,Christian von Mering,Peer Bork +12 more
TL;DR: The third version of the eggNOG database contains non-supervised orthologous groups constructed from 1133 organisms, doubling the number of genes with orthology assignment compared to eggNog v2 and the newly designed web page is considerably faster with more functionality.
The axolotl genome and the evolution of key tissue formation regulators
Sergej Nowoshilow,Sergej Nowoshilow,Sergej Nowoshilow,Siegfried Schloissnig,Ji-Feng Fei,Andreas Dahl,Andy Wing Chun Pang,Martin Pippel,Sylke Winkler,Alex Hastie,George R. Young,Juliana G. Roscito,Francisco Falcon,Dunja Knapp,Sean Powell,Alfredo Cruz,Han Cao,Bianca Habermann,Michael Hiller,Elly M. Tanaka,Elly M. Tanaka,Elly M. Tanaka,Eugene W. Myers +22 more
TL;DR: The sequencing and assembly of the 32-gigabase-pair axolotl genome is reported using an approach that combined long-read sequencing, optical mapping and development of a new genome assembler (MARVEL).
The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms
Markus A. Grohme,Siegfried Schloissnig,Andrei Rozanski,Martin Pippel,George R. Young,Sylke Winkler,Holger Brandl,Ian Henry,Andreas Dahl,Sean Powell,Michael Hiller,Eugene W. Myers,Jochen C. Rink +12 more
TL;DR: The genome assembly of S. mediterranea is reported, using long-read sequencing and a de novo assembler enhanced for low-complexity reads to provide a key model system resource that will be useful for studying regeneration and the evolutionary plasticity of core cell biological mechanisms.
Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos
Zhenhai Du,Hui Zheng,Yumiko K Kawamura,Ke Zhang,Johanna Gassler,Sean Powell,Qianhua Xu,Zili Lin,Kai Xu,Qian Zhou,Evgeniy A. Ozonov,Nathalie Véron,Bo Huang,Lijia Li,Guang Yu,Ling Liu,Wan Kin Au Yeung,Peizhe Wang,Lei Chang,Qiujun Wang,Aibin He,Yujie Sun,Jie Na,Qing-Yuan Sun,Hiroyuki Sasaki,Kikuë Tachibana,Kikuë Tachibana,Antoine H.F.M. Peters,Antoine H.F.M. Peters,Wei Xie +29 more
TL;DR: A critical role of Polycomb is revealed in regulating chromatin architecture during mammalian oocyte growth and early development using low-input Hi-C (genome-wide chromatin conformation capture) data.
133