Sean Pelkowski
University of Rochester
6 Papers
3 Citations
Sean Pelkowski is an academic researcher from University of Rochester. The author has contributed to research in topics: Biology & Thigmotaxis. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Sean Pelkowski include Brown University.
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Papers
On the edge: Pharmacological evidence for anxiety-related behavior in zebrafish larvae
TL;DR: The results suggest that the edge preference in zebrafish larvae is a measure of anxiety and further illustrate that the pharmaceuticals used in the study have different mechanisms of action.
207
A novel high-throughput imaging system for automated analyses of avoidance behavior in zebrafish larvae
Sean Pelkowski,Mrinal Kapoor,Holly A. Richendrfer,Xingyue Wang,Ruth M. Colwill,Robbert Creton +5 more
TL;DR: Results indicate that the seven-day-old zebrafish larvae respond specifically to movement, rather than color, size, or local changes in light intensity, which may be used to screen for genetic and environmental factors that cause developmental brain disorders and for novel drugs that could prevent or treat these disorders.
133
Developmental sub-chronic exposure to chlorpyrifos reduces anxiety-related behavior in zebrafish larvae.
TL;DR: It is proposed that sub-chronic chlorpyrifos exposure interferes with the development of anxiety-related behaviors in zebrafish larvae, and provides a good starting point for examination of the molecular, cellular, developmental, and neural mechanisms that are affected by environmentally relevant concentrations of organophosphate pesticides.
98
Sex-Dependent and Non-Monotonic Enhancement and Unmasking of Methylmercury Neurotoxicity by Prenatal Stress
Hiromi I. Weston,Marissa Sobolewski,Joshua L. Allen,Doug D. Weston,Katherine Conrad,Sean Pelkowski,Gene E. Watson,Grazyna Zareba,Deborah A. Cory-Slechta +8 more
TL;DR: Findings demonstrate sex-dependent and non-monotonic effects of developmental MeHg exposure that can be unmasked or enhanced by PS, particularly for behavioral outcomes in females, but for both sexes in neurochemical changes, that were observed at MeHG exposure concentrations that did not influence either reproductive outcomes or maternal behavior.
24
Unruptured intracranial aneurysms and life insurance underwriting
Eugene Scharf,Sean Pelkowski,Bogachan Sahin +2 more
- 01 Jun 2017
TL;DR: A perspective on insurance underwriting in individuals with unruptured intracranial aneurysms is provided and points for clinicians to consider when counseling patients seeking screening are offered.
5