Sean Myles
Dalhousie University
71 Papers
93 Citations
Sean Myles is an academic researcher from Dalhousie University. The author has contributed to research in topics: Population & Biology. The author has an hindex of 35, co-authored 68 publications. Previous affiliations of Sean Myles include Nova Scotia Agricultural College & Cornell University.
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Papers
Association Mapping: Critical Considerations Shift from Genotyping to Experimental Design
Sean Myles,Jason A. Peiffer,Patrick J. Brown,Elhan S. Ersoz,Zhiwu Zhang,Denise E. Costich,Denise E. Costich,Edward S. Buckler,Edward S. Buckler +8 more
TL;DR: This review provides thoughts on finding the optimal experimental mix of association mapping using unrelated individuals and controlled crosses to identify the genes underlying phenotypic variation.
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How culture shaped the human genome: bringing genetics and the human sciences together
TL;DR: The considerable potential for cross-disciplinary exchange is highlighted to provide novel insights into how culture has shaped the human genome, supported by recent analyses of human genetic variation, which reveal that hundreds of genes have been subject to recent positive selection.
863
Genetic structure and domestication history of the grape.
Sean Myles,Adam R. Boyko,Christopher L. Owens,Patrick J. Brown,Fabrizio Grassi,Mallikarjuna K. Aradhya,Bernard Prins,Andy Reynolds,Jer Ming Chia,Doreen Ware,Doreen Ware,Carlos Bustamante,Edward S. Buckler +12 more
TL;DR: It is proposed that the adoption of vegetative propagation was a double-edged sword: Although it provided a benefit by ensuring true breeding cultivars, it also discouraged the generation of unique cultivars through crosses.
Agriculture: Feeding the future
Susan R. McCouch,Gregory J. Baute,James M. Bradeen,P. J. Bramel,Peter K. Bretting,Edward S. Buckler,Edward S. Buckler,John M. Burke,David Charest,Sylvie Cloutier,Glenn Cole,Hannes Dempewolf,Michaël Dingkuhn,Michaël Dingkuhn,Catherine Feuillet,Paul Gepts,Dario Grattapaglia,Luigi Guarino,Scott A. Jackson,Sandra Knapp,Peter Langridge,Amy Lawton-Rauh,Qui Lijua,Charlotte Lusty,Todd P. Michael,Sean Myles,Ken Naito,Randall L. Nelson,Randall L. Nelson,Reno Pontarollo,Christopher M. Richards,Loren H. Rieseberg,Jeffrey Ross-Ibarra,Steve Rounsley,Ruaraidh Sackville Hamilton,Ulrich Schurr,Nils Stein,Norihiko Tomooka,Esther van der Knaap,David L. Van Tassel,Jane Toll,José Francisco Montenegro Valls,Rajeev K. Varshney,Judson A Ward,Robbie Waugh,Peter Wenzl,Daniel Zamir +46 more
TL;DR: Humanity depends on fewer than a dozen of the approximately 300,000 species of flowering plants for 80% of its caloric intake and capitalize on only a fraction of the genetic diversity that resides within each of these species.
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LinkImpute: Fast and Accurate Genotype Imputation for Nonmodel Organisms
TL;DR: LinkImpute is introduced, a software package based on a k-nearest neighbor genotype imputation method, LD-kNNi, which is designed for unordered markers and exploits the fact that markers useful for imputation often are not physically close to the missing genotype but rather distributed throughout the genome.