Sean Collins
9 Papers
Sean Collins is an academic researcher. The author has contributed to research in topics: Medicine & Placebo. The author has an hindex of 4, co-authored 5 publications.
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Papers
Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19: A Randomized Clinical Trial.
Susanna Naggie,David R. Boulware,Christopher J. Lindsell,Thomas G. Stewart,Alex Slandzicki,Stephen C. Lim,J. Cohen,D. Kavtaradze,Arch P. Amon,Ahab Gabriel,Nina T. Gentile,G. Michael Felker,Dushyantha Jayaweera,Matthew W. McCarthy,Mark S. Sulkowski,Russell L. Rothman,Sybil Wilson,Allison DeLong,April Remaly,Rhonda Wilder,Sean Collins,Sarah E. Dunsmore,Stacey J Adam,Florence Thicklin,George Hanna,Adit A. Ginde,Mario Castro,Kathleen M. McTigue,Elizabeth Shenkman,Adrian F. Hernandez,William Vincent,Raina Vincent,Ray Bianchi,Jen Premas,Diana Cordero-Loperena,Evelyn Rivera,Madhu Gupta,Greg Karawan,Carey Ziomek,Joseph Arena,Sonaly DeAlmeida,Soroush Ramin,Jaya Nataraj,Michael Paasche-Orlow,Lori Henault,K. Waite,David Miller,Ginger Brounce,Constance George-Adebayo,Adeolu Adebayo,Jessica Wallan,Claudia Vogel,Sebastian Munoz,Cassandra Watson,David E. Singleton,Maria Rivon,Amanda Sevier,Arnold Del Pilar,Amber Spangler,Sohail Rao,Luis L. Cantu,A. Krishna,Kathy M. Evans,Tylene Falkner,Brandi Kerr,R. Beecher. Spees,Mailyn Marta,Amanda T. Harrington,Rowena J. Dolor,Madison Frazier,Lorraine Vergara,Jessica Wilson,Valencia Burruss,Teri Hurst,Ighovwerha Ofotokun,Pauline Rebolledo,Rajesh Prabhu,K. Klicka,Amber Lightfeather,Vicki M. James,Marc Stanley Rogers,Pradeep Parihar,De'Ambra Torress,Chukwuemeka Oragwu,Ngozi C Oguego,Rajesh Pillai,M. Juma,Emad Ghaly,Dafer Al-Haddadin,Courtney Ramirez,Gammal Hassanien,Samah M. Ismail,Andrew L Meltzer,Seamus Moran,Scott S Brehaut,Angela Roche,Manisha Mehta,Nicole Koppinger,J. Baez,I.D. Pagan,D. Abdelsayed,Mina Aziz,Philip G. Robinson,Julie Linh Nguyen,Victoria Pardue,Lisa D. Hammons,J. Ruiz-Unger,Susan Natacha Gonzalez,Lionel Reyes,John J. Cienki,Gisselle A. Jimenez,Matthew Wong,Ying Yuan,Jenny Li,Jeremy Szeto,Lauren Stelmash,Daniel Haight,Deryl Lamb,Amron Harper,Nancy Pyram-Bernard,A.F. Quintero,Eftim J. Adhami,J. María,Diksha Paudel,Oksana Raymond,J. Summers,T Turner,Leslie A. Lenert,Sam Gallegos,E. Szwast,Ahsan A. Abdulghani,Pravin Vasoya,Conrad Miller,Hawa Wiley,Nirav Shah,Tovah Klein,Julie Castex,Phillip Feliciano,Jacqueline Olivo,Marian Hosney Ghaly,Zainub Javed,Alexandra Nawrocki,Anthony Vecchiarelli,Nikki Vigil,Vijay Cherukuri,Erica Burden,Dawn M Linn,L.H. Fisher,Vijay Patel,Praksha Patel,Yuti Patel,Leonard Ellison,Jeffrey Harrison,Binod Shah,Sugata Shah,Upinder Singh,Julie M. Donahue,Yasmin Jazayeri,Anita Gupta,N. Chandrasekar,Beth Moritz,Tabitha Fortt,Anisa Fortt,Ingrid Jones-Ince,Alix McKee,Christy Schattinger,Jason R. Wilson,Brenda Farlow,Lillian Finlaw,Randall Richwine,Tearani Williams,Penny Paizer,Lisa Carson,Edward A. Michelson,Danielle M. Austin,Sangeeta Khetpal,T. Cantrell,Drew Franklin,Karis Marshall,Arvind Mahadevan,M. Rosequist,Martin Gnoni,Crystal Daffner,Carla VandeWeerd,Mark S. Roberts,Mark D’Andrea,Wayne Swink,Margaret V. Powers-Fletcher,Sylvere Mukunzi,Jamie Hensley,Brittney R. Manning,Carmen Isache,Jennifer Davis Bowman,Angelique Callaghan-Brown,T. Scott,Tiffany E Schwasinger-Schmidt,Ashlie Cornejo,Maria Almanzar,Letty Ginsburg,Americo Hajaz,Carolyn T. Bramante,Matthew L Robinson,Michelle Lynn Seithel,Akira Sekikawa,Emily Klawson,Luis Z Ostrosky,Virginia E Umana,Thomas Patterson,Robin Tragus,Patrick E. H. Jackson,C. Hallowell,Heather M. Haughey,Bhavna Vaidya-Tank,Cameron Gould,Parul Goyal,Carly Gatewood,John Williamson,Hannah M Seagle,Elizabeth Salsgiver,Edward R. Armas,Jhonsai Cheng,Priscilla Huerta,Julia Garcia-Diaz,David Aamodt,JaMario Ayers,Jessica B. Collins,John Graves,James Grindstaff,Jessica Lai,I. López,Jessica S Marlin,Alyssa Merkel,S. A. Nwosu,Savannah Obregon,Dirk Orozco,Yoli Perez-Torres,Nelson Prato,Colleen Ratcliff,Max Rhode,Jana K. Shirey-Rice,Krista Vermillion,Hsi-Nien Tan,Seibert Tregoning,Meghan Vance,Amber Vongsamphanh,Mary Weir,Nicole M. Zaleski,Samuel A. Bozzette,Gene Passamani +248 more
TL;DR: In this article , the authors evaluated the effectiveness of ivermectin at a maximum targeted dose of 600 μg/kg daily for 6 days, compared with placebo, for the treatment of early mild to moderate COVID-19.
Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor-Biased Ligand in Adults With COVID-19: Two Randomized Clinical Trials.
Wesley H. Self,Matthew S. Shotwell,Kevin W Gibbs,Marjolein de Wit,D. Clark Files,Michelle Harkins,Kristin M. Hudock,Lisa H. Merck,Ari Moskowitz,Krystle Apodaca,Aaron N. Barksdale,Basmah Safdar,Ali Javaheri,Jeffrey M. Sturek,Harry M Schrager,Nicole M. Iovine,Ivor S. Douglas,Joseph E. Levitt,Laurence W. Busse,Adit A. Ginde,Sam Brown,David N. Hager,Katherine L. Boyle,Abhijit Duggal,Akram Khan,Michael J. Lanspa,Peter Chen,Michael A. Puskarich,Derek J Vonderhaar,Lokesh Venkateshaiah,Nina T. Gentile,Yves Rosenberg,James Troendle,Amanda J. Bistran-Hall,Josh DeClercq,Robert R. Lavieri,Meghan Morrison Joly,Jill M. Pulley,Todd W. Rice,Jonathan S. Schildcrout,Matthew W. Semler,Lei Wang,Gordon R. Bernard,Sean Collins +43 more
TL;DR: In this paper , the authors evaluated the efficacy and safety of RAS modulation using two investigational RAS agents, TXA-127 (synthetic angiotensin [1-7]) and TRV-027 (an angio-ensin II type 1 receptor-biased ligand), that are hypothesized to potentiate the action of angioensin (1 − 7) and mitigate the action (2 − 5) and may be an important contributor to COVID-19 pathophysiology.
Evaluating automated electronic case report form data entry from electronic health records
A. Cheng,Mary Katy Banasiewicz,Jakea Johnson,Lina Sulieman,Nan Kennedy,Francesco Delacqua,Adam A. Lewis,Meghan Morrison Joly,Amanda J. Bistran-Hall,Sean Collins,Wesley H. Self,Matthew S. Shotwell,Christopher J. Lindsell,Paul A. Harris +13 more
TL;DR: In this article , a test of automated EHR-to-CRF data transfer for 40 participants in a clinical trial of hospitalized COVID-19 patients was conducted, and the authors determined which coordinator-entered data could be automated from the EHR (coverage), and the frequency with which the values from the automated Ehr feed and values entered by study personnel for the actual study matched exactly (concordance).
Higher-Dose Fluvoxamine and Time to Sustained Recovery in Outpatients With COVID-19: The ACTIV-6 Randomized Clinical Trial.
Thomas G Stewart,Pauline Rebolledo,Ahmad Mourad,Christopher J Lindsell,David R Boulware,Matthew W McCarthy,Florence Thicklin,Idania T Garcia Del Sol,Carolyn T Bramante,Leslie A Lenert,Stephen Lim,John Williamson,Orlando Quintero Cardona,Tiffany Schwasinger-Schmidt,Adit A. Ginde,Mario Castro,Dushyantha Jayaweera,Mark Sulkowski,Nina Gentile,K. J. Mctigue,G. M. Felker,Allison DeLong,Rhonda Wilder,Russell L Rothman,Sean Collins,Sarah E. Dunsmore,Stacey J Adam,George Hanna,Elizabeth Shenkman,Adrian F. Hernandez,S. Naggie +30 more
- 17 Nov 2023
TL;DR: Among outpatients with mild to moderate CO VID-19, treatment with fluvoxamine does not reduce duration of COVID-19 symptoms, and unadjusted median time to sustained recovery was 10 days in both the intervention and placebo groups.
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Randomized controlled trial of urinE chemiStry guided aCute heArt faiLure treATmEnt (ESCALATE): Rationale and design.
Zachary L. Cox,Hasan K. Siddiqi,Lynne W. Stevenson,Brian Bales,Jin Hee Han,Kimberly Hart,Brant Imhoff,Juan Betuel Ivey-Miranda,Cathy A. Jenkins,JoAnn Lindenfeld,Matthew S. Shotwell,Karen F. Miller,Henry Ooi,Veena Rao,Kelly Schlendorf,Wesley H. Self,Edward D. Siew,Alan B. Storrow,Ryan R. Walsh,Jesse O. Wrenn,Jeffrey M. Testani,Sean Collins +21 more
TL;DR: The ESCALATE trial is designed to test the hypothesis that protocolized diuretic therapy guided by spot urine chemistry through completion of intravenous diuresis will be superior to usual care and improve outcomes over the 14 days following randomization.
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