Scott Cookson
University of California, San Diego
11 Papers
134 Citations
Scott Cookson is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Population & Cell growth. The author has an hindex of 6, co-authored 11 publications. Previous affiliations of Scott Cookson include University of California.
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Papers
A fast, robust and tunable synthetic gene oscillator
Jesse Stricker,Scott Cookson,Matthew R. Bennett,William H. Mather,Lev S. Tsimring,Jeff Hasty +5 more
TL;DR: An engineered genetic oscillator in Escherichia coli is described that is fast, robust and persistent, with tunable oscillatory periods as fast as 13 min, and Computational modelling demonstrates that the key design principle for constructing a robust oscillator is a time delay in the negative feedback loop.
Biomechanical ordering of dense cell populations
TL;DR: A continuum model of collective cell dynamics based on equations for local cell density, velocity, and the tensor order parameter is developed and used to elucidate the mechanism of cell ordering and quantify the relationship between the dynamics of cell proliferation and the spatial structure of the population.
Monitoring dynamics of single-cell gene expression over multiple cell cycles.
TL;DR: This work utilizes microfabrication to construct a Tesla microchemostat that permits single-cell fluorescence imaging of gene expression over many cellular generations and explores the evolution of single- cell gene expression and cycle time as a function of generation.
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Gene Transfer in Leptolyngbya sp. Strain BL0902, a Cyanobacterium Suitable for Production of Biomass and Bioproducts
Arnaud Taton,Ewa T. Lis,Dawn M. Adin,Guogang Dong,Scott Cookson,Steve A. Kay,Susan S. Golden,James W. Golden +7 more
TL;DR: Growth properties and genetic tools position Leptolyngbya BL0902 as a model cyanobacterial production strain and conjugal transfer from Escherichia coli of a plasmid based on RSF1010 and expression of spectinomycin/streptomycin resistance and yemGFP reporter transgenes are demonstrated.
Monitoring dynamics of single-cell gene expression over multiple cell cycles
Scott Cookson,Natalie Ostroff,Wyming Lee Pang,Dmitri Volfson,Jeff Hasty +4 more
- 01 Jan 2006
TL;DR: This work utilizes microfabrication to construct a Tesla microchemostat that permits single-cell fluorescence imaging of gene expression over many cellular generations and explores the evolution of single- cell gene expression and cycle time as a function of generation.