Satabdee Mohapatra
Tel Aviv University
8 Papers
17 Citations
Satabdee Mohapatra is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 3, co-authored 4 publications.
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Papers
Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of α-Synuclein Amyloids in Parkinson's Disease.
TL;DR: The conjugates of Mannitol and naphthoquinone-tryptophan were found to be have low cytotoxicity and reduced toxicity of α-Syn toward SH-SY5Y neuroblastoma cells and can be attractive scaffold for the development of therapeutic agents for PD.
Inhibitory Effect of Naphthoquinone-Tryptophan Hybrid towards Aggregation of PAP f39 Semen Amyloid.
Guru KrishnaKumar Viswanathan,Satabdee Mohapatra,Ashim Paul,Elad Arad,Raz Jelinek,Ehud Gazit,Daniel L. Segal +6 more
TL;DR: This study shows that the naphthoquinone tryptophan (NQTrp) hybrid molecule significantly inhibited PAP f39 aggregation in vitro in a dose-dependent manner as observed from the ThT assay, ANS assay, and transmission electron microscopy imaging.
15
Copper drives prion protein phase separation and modulates aggregation
Mariana J. do Amaral,Aline Ribeiro Passos,Satabdee Mohapatra,Taiana Souza Lopes da Silva,Renato S. Carvalho,Marcius S. Almeida,Anderson de Sá Pinheiro,Susanne Wegmann,Yraima Cordeiro +8 more
TL;DR: In this article , the role of Cu2+ and oxidation in prion protein condensation and aggregation was investigated using multiple biophysical and biochemical methods, and it was found that Cu 2+ promotes PrP condensation at the cell surface and in vitro through co-partitioning.
Biomolecular condensation involving the cytoskeleton
TL;DR: A review of the current literature on protein condensation processes related to the actin, tubulin, and intermediate filament cytoskeleton, and discuss some of them in the context of neurobiology can be found in this paper .
11
Dual concentration-dependent effect of ascorbic acid on PAP(248-286) amyloid formation and SEVI-mediated HIV infection.
Satabdee Mohapatra,Guru KrishnaKumar Viswanathan,Lukas Wettstein,Elad Arad,Ashim Paul,Vijay Kumar,Raz Jelinek,Jan Münch,Daniel L. Segal +8 more
- 07 Oct 2021
TL;DR: Biophysical insight is provided into the effect of AA, an important seminal component, on SEVI fibrillation which might impact amyloid formation kinetics, thereby modulating the biological activity of semen amyloids.