Sarkis K. Mazmanian
California Institute of Technology
175 Papers
620 Citations
Sarkis K. Mazmanian is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Biology & Microbiome. The author has an hindex of 68, co-authored 143 publications. Previous affiliations of Sarkis K. Mazmanian include University of Chicago & Brigham and Women's Hospital.
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Papers
Patent
Diagnosis and treatment of autism spectrum disorder
Elaine Y. Hsiao,Sarkis K. Mazmanian,Paul H. Patterson,Sara Mcbride +3 more
- 28 Aug 2013
TL;DR: In this paper, compositions, systems, and methods for diagnosing and treatment of subjects suffering from anxiety, autism spectrum disorder (ASD), or a pathological condition with one or more of the symptoms of ASD are presented.
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Emerging evidence linking the gut microbiome to neurologic disorders
TL;DR: Uncovering mechanisms that are utilized by the microbiome to mediate gut–brain connections may provide novel opportunities to target therapies to the gut in order to treat neurologic disorders.
Human microbiome science: vision for the future, Bethesda, MD, July 24 to 26, 2013
Jacques Ravel,Martin J. Blaser,Jonathan Braun,Eric M. Brown,Frederic D. Bushman,Eugene B. Chang,Julian Davies,Kathryn G. Dewey,Timothy G. Dinan,Maria Gloria Dominguez-Bello,Susan E. Erdman,B. Brett Finlay,Wendy S. Garrett,Gary B. Huffnagle,Curtis Huttenhower,Janet K. Jansson,Ian B. Jeffery,Christian Jobin,Alexander Khoruts,Heidi H. Kong,Johanna W. Lampe,Ruth E. Ley,Dan R. Littman,Sarkis K. Mazmanian,David A. Mills,Andrew S. Neish,Elaine O. Petrof,David A. Relman,Rosamond Rhodes,Peter J. Turnbaugh,Vincent B. Young,Rob Knight,Owen White +32 more
TL;DR: What is needed for human microbiome research to move forward and deliver medical translational applications is described.
Multiple sclerosis-associated changes in the composition and immune functions of spore-forming bacteria
Egle Cekanaviciute,Anne-Katrin Pröbstel,Anna Thomann,Tessel F. Runia,Patrizia Casaccia,Patrizia Casaccia,Ilana Katz Sand,Elizabeth Crabtree,Sneha Singh,John P. Morrissey,Patrick Barba,Refujia Gomez,Rob Knight,Sarkis K. Mazmanian,Jennifer Graves,Bruce A.C. Cree,Scott S. Zamvil,Sergio E. Baranzini,Sergio E. Baranzini +18 more
TL;DR: It is shown that while small differences exist between the microbiomes of MS patients and healthy subjects, these differences are exacerbated in the chloroform resistant fraction, and it is demonstrated that, when purified from MS patients, this fraction is associated with impaired immunomodulatory responses in vitro.
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Human microbiome science: vision for the future,
Jacques Ravel,Martin J. Blaser,Jonathan Braun,Eric M. Brown,Frederic D. Bushman,Eugene B. Chang,Julian Davies,Kathryn G. Dewey,Timothy G. Dinan,Maria Gloria Dominguez-Bello,Susan E. Erdman,B. Brett Finlay,Wendy S. Garrett,Gary B. Huffnagle,Curtis Huttenhower,Janet K. Jansson,Ian B. Jeffery,Christian Jobin,Alexander Khoruts,Heidi H. Kong,Johanna W. Lampe,Ruth E. Ley,Dan R. Littman,Sarkis K. Mazmanian,David A. Mills,Andrew S. Neish,Elaine O. Petrof,David A. Relman,Rosamond Rhodes,Peter J. Turnbaugh,Vincent B. Young,Rob Knight,Owen White +32 more
- 01 Jan 2014
TL;DR: What is needed for human microbiome research to move forward and deliver medical translational applications is described.