Sarah Schlotter
Harvard University
10 Papers
Sarah Schlotter is an academic researcher from Harvard University. The author has contributed to research in topics: Virus & Spin-½. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Sarah Schlotter include Massachusetts Institute of Technology.
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Papers
Epigenetic Activation of the EBV Protein Kinase Determines Antiviral Drug Response in Central Nervous System Lymphoma
C. Weigel,H. Klimaszewski,S. Addissie,Sarah Schlotter,F. Tounkara,J. P. Dugan,B. M. Haverkos,Linda Villagomez,M. Lustberg,P. Porcu,T. Voorhees,M. A. Caligiuri,G. Bumgardner,C. C. Oakes,R. Baiocchi +14 more
TL;DR: Epigenetic activation of EBV protein kinase BGLF4 via DNA demethylation is crucial for antiviral drug response in CNS lymphoma, with implications for determining treatment sensitivity in patients with this aggressive and poorly prognostic disease.
Targeting EBV Encoded Viral Kinases with GCV, AZT, Rituximab and Dexamethasone (GARD) Results in Durable Responses in Patients with CNS Lymphoproliferative Disease
Haley L Klimaszewski,Christoph Weigel,Selamawit Addissie,Sarah Schlotter,Tounkara Fode,James P. Dugan,Bradley M. Haverkos,Linda Villagomez,Mark E. Lustberg,Pierluigi Porcu,Timothy J Voorhees,Michael A. Caligiuri,Christopher C. Oakes,Ginny L. Bumgardner,Robert A. Baiocchi +14 more
TL;DR: unique viral epigenetic states leading to expression of antiviral drug targets in an array of EBV+ CNS-LPD revealed in an IRB-approved, retrospective review of patients treated with GARD between 1998-2022.
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Imaging the Spin Texture of a Skyrmion Under Ambient Conditions Using an Atomic-Sized Sensor
Yuliya Dovzhenko,Francesco Casola,Sarah Schlotter,Tony X. Zhou,Felix Büttner,Ronald L. Walsworth,Geoffrey S. D. Beach,Amir Yacoby +7 more
TL;DR: In this article, the authors used the single electron spin of a Nitrogen-Vacancy (NV) center in diamond to perform scanning magnetometry of skyrmions in Pt/Co/Ta multilayers under ambient conditions.
Measurement of interfacial Dzyaloshinskii-Moriya interaction from static domain imaging
Parnika Agrawal,Felix Büttner,Ivan Lemesh,Sarah Schlotter,Sarah Schlotter,Geoffrey S. D. Beach +5 more
TL;DR: In this article, the authors used a recently developed analytical model of stripe domain widths in perpendicularly magnetized multilayers to extract the DMI from domain images combined with magnetometry data.
Abstract LB422: Specific activation of the Epstein-Barr Virus BGLF4 locus via lowered DNA methylation in EBV-associated CNS lymphoproliferative disease
Christoph Weigel,Haley Klimaszewski,Selamawit Addissie,Sarah Schlotter,Fodé Tounkara,James P. Dugan,Bradley M. Haverkos,Linda Villagomez,Mark E. Lustberg,Pierluigi Porcu,Timothy Voorhees,Michael A. Caligiuri,Ginny Bumgardner,Christopher C. Oakes,Robert A. Baiocchi +14 more
TL;DR: The results provide the molecular basis for expression of BGLF4 in CNS-LPD by showing decreased promotor DNA methylation and identified specific BGLF4 methylation sites that hold promise as potential DNA biomarkers for EBV+ CNS-LPD.