Sarah Rush
Boston Children's Hospital
19 Papers
37 Citations
Sarah Rush is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Health care. The author has an hindex of 7, co-authored 13 publications. Previous affiliations of Sarah Rush include University of Colorado Denver.
Chat about Author
Papers
Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures
Adrienne Johnson,Eric Allan Severson,Jo-Anne Vergilio,Julia A. Elvin,James Suh,Sugganth Daniel,Mandy Covert,Garrett M. Frampton,Sigmund Hsu,Glenn J. Lesser,Kimberly Stogner-Underwood,Ryan T. Mott,Sarah Rush,Jennifer Stanke,Sonika Dahiya,James Sun,Prasanth Reddy,Zachary R. Chalmers,Rachel L. Erlich,Yakov Chudnovsky,David Fabrizio,Alexa B. Schrock,Siraj M. Ali,Vincent A. Miller,Philip J. Stephens,Jeffrey S. Ross,John R. Crawford,Shakti H. Ramkissoon +27 more
TL;DR: The most common alterations across diagnosis and anatomic location are explored and tumor mutational burden and associated genetic factors that may predispose patients to developing a hypermutator phenotype are discussed.
254
Pediatric Brainstem Gangliogliomas Show BRAFV600E Mutation in a High Percentage of Cases
Andrew M. Donson,Bette K. Kleinschmidt-DeMasters,Dara L. Aisner,Lynne T. Bemis,Diane Birks,Jean M. Mulcahy Levy,Amy A. Smith,Michael H. Handler,Nicholas K. Foreman,Sarah Rush +9 more
TL;DR: BRAFV600E‐targeted therapeutics should be a consideration for the high percentage of pediatric brainstem GGs refractory to conventional therapies.
63
Diagnostic delay and morbidity of central nervous system tumors in children and young adults: a pediatric hospital experience
TL;DR: An institution aimed to identify diagnostic delays, morbidity and mortality, and specific barriers that may exist within the authors' specific healthcare system that result in diagnostic delay, as well as a decrease in associated morbidity.
36
Pediatric posterior fossa ganglioglioma: unique MRI features and correlation with BRAF V600E mutation status
TL;DR: Compared with ST GGs, PF GGs are expansile, infiltrative, show dorsal predominant “paintbrush” enhancement, are not amenable to gross total resection, and have worse progression-free survival and mortality.
28
Retrospective analysis of combination carboplatin and vinblastine for pediatric low-grade glioma.
Anandani Nellan,Anandani Nellan,Erin Wright,Kristen Campbell,Kurtis D. Davies,Andrew M. Donson,Vladimir Amani,Alexis Judd,Molly Hemenway,Jennifer L Raybin,Nicholas K. Foreman,Sarah Rush,Kathleen Dorris +12 more
TL;DR: C/VBL achieves similar EFS rates to other single-agent and combination cytotoxic chemotherapy regimens for pediatric LGG with manageable toxicities and best therapy response was partial response in nine patients and stable disease in twenty-five patients.
19