Sarah Geller
University of Lausanne
19 Papers
28 Citations
Sarah Geller is an academic researcher from University of Lausanne. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 7, co-authored 11 publications. Previous affiliations of Sarah Geller include François Rabelais University.
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Papers
Tanycytes Regulate Lipid Homeostasis by Sensing Free Fatty Acids and Signaling to Key Hypothalamic Neuronal Populations via FGF21 Secretion.
Sarah Geller,Yoan Arribat,Citlalli Netzahualcoyotzi,Sylviane Lagarrigue,Lionel Carneiro,Lianjun Zhang,Francesca Amati,Isabel C. Lopez-Mejia,Luc Pellerin,Luc Pellerin +9 more
TL;DR: Tanycytes sense free fatty acids to maintain body lipid homeostasis through Fgf21 signaling within the hypothalamus, and deletion of tanycytic FgF21 triggers an increase in lipolysis.
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GnRH neurons recruit astrocytes in infancy to facilitate network integration and sexual maturation
Giuliana Pellegrino,Marion Martin,Cecile Allet,Tori Lhomme,Sarah Geller,Delphine Franssen,Virginie Mansuy,Maria Manfredi-Lozano,Adrian Coutteau-Robles,Virginia Delli,S. Rasika,Danièle Mazur,Anne Loyens,Manuel Tena-Sempere,Manuel Tena-Sempere,Juergen Siepmann,François P. Pralong,Philippe Ciofi,Philippe Ciofi,Gabriel Corfas,Anne-Simone Parent,Sergio R. Ojeda,Ariane Sharif,Vincent Prevot +23 more
TL;DR: In this article, a neuron-to-neural-progenitor communication pathway was shown to be a basic component of a complex set of mechanisms used by the neuroendocrine brain to control sexual maturation.
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Hypothalamic sensing of ketone bodies after prolonged cerebral exposure leads to metabolic control dysregulation.
Lionel Carneiro,Sarah Geller,Audrey Hébert,Cendrine Repond,Xavier Fioramonti,Corinne Leloup,Luc Pellerin +6 more
TL;DR: It is confirmed that ketone bodies reaching the brain stimulates food intake and evidence is provided that a prolonged hyperketonemia leads to a dysregulation of energy homeostasis control mechanisms.
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GnRH Episodic Secretion Is Altered by Pharmacological Blockade of Gap Junctions: Possible Involvement of Glial Cells
Caroline Pinet-Charvet,Sarah Geller,Elodie Desroziers,Monique Ottogalli,Didier Lomet,Christine Georgelin,Yves Tillet,Isabelle Franceschini,Pascal Vaudin,Anne Duittoz +9 more
TL;DR: This study investigated whether glial cell communication through gap junctions plays a role in GnRH neuron activity and secretion in the mouse and found that in vitro glial cells forming the microenvironment of GnRH neurons expressed connexin-43 and displayed functional gapjunctions.
Neuroprotective effect of rLosac on supplement-deprived mouse cultured cortical neurons involves maintenance of monocarboxylate transporter MCT2 protein levels.
Miryam P. Alvarez‐Flores,Miryam P. Alvarez‐Flores,Audrey Hébert,Cathy Gouelle,Sarah Geller,Ana Marisa Chudzinski-Tavassi,Luc Pellerin,Luc Pellerin +7 more
TL;DR: The observations suggest that rLosac promotes cell viability in stressed (B27 supplement‐deprived) neurons by facilitating the use of lactate as energy substrate via the preservation of MCT2 protein expression.
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