Sarah Dawson
University of Cambridge
12 Papers
52 Citations
Sarah Dawson is an academic researcher from University of Cambridge. The author has contributed to research in topics: Randomized controlled trial & Population. The author has an hindex of 9, co-authored 11 publications. Previous affiliations of Sarah Dawson include Cambridge University Hospitals NHS Foundation Trust.
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Papers
Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.
John A. Todd,Marina Evangelou,Antony J. Cutler,Marcin L. Pekalski,Neil Walker,Helen Stevens,Linsey Porter,Deborah J. Smyth,Daniel B. Rainbow,Ricardo C. Ferreira,Laura Esposito,Kara Hunter,Kevin W. Loudon,Kathryn Irons,Jennie H M Yang,Charles J.M. Bell,Helen Schuilenburg,James Heywood,Ben Challis,Sankalpa Neupane,Pamela Clarke,Gillian Coleman,Sarah Dawson,Donna Goymer,Katerina Anselmiova,Jane Kennet,Judy Brown,Sarah L Caddy,Jia Lu,Jane Greatorex,Ian Goodfellow,Chris Wallace,Timothy Tree,Mark L. Evans,Adrian Mander,Simon Bond,Simon Bond,Linda S. Wicker,Frank Waldron-Lynch +38 more
TL;DR: A statistical and systematic approach was taken by analysing the pharmacokinetics and pharmacodynamics of single doses of subcutaneous aldesleukin in the Adaptive Study of IL-2 Dose on Regulatory T Cells in Type 1 Diabetes, a single centre, non-randomised, open label, adaptive dose-finding trial with 40 adult participants with recently diagnosed T1D.
Identification of pathologically insignificant prostate cancer is not accurate in unscreened men.
Greg Shaw,Benjamin Thomas,Sarah Dawson,G Srivastava,Sarah L. Vowler,Vincent Gnanapragasam,Nimish Shah,Anne Y. Warren,David E. Neal +8 more
TL;DR: In the unscreened population, tools designed to identify insignificant PC are inaccurate, and Detection of a wider size range of prostate tumours in the un screened population may contribute to relative inaccuracy.
Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles
Laura Esposito,Kara Hunter,Jan Clark,Daniel B. Rainbow,Helen Stevens,Jennifer Denesha,Simon Duley,Sarah Dawson,Gillian Coleman,Sarah Nutland,Gwynneth L. Bell,Carla Moran,Marcin L. Pekalski,John A. Todd,Linda S. Wicker +14 more
TL;DR: It is demonstrated that the sCTLA-4 protein is secreted at low levels following the activation of primary human CD4+ T cells and is increased only rarely in the serum of autoimmune patients.
Detailed analysis of operating time learning curves in robotic prostatectomy by a novice surgeon.
TL;DR: In this article, a prospective ethically approved database was used to evaluate the operating times of each individual surgical step, in the first 150 RALP cases performed independently by a robotic-naive laparoscopic surgeon.
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Detection of colorectal dysplasia using fluorescently labelled lectins
Joe Chin-Hun Kuo,Ashraf E.K. Ibrahim,Sarah Dawson,Deepak Parashar,William J. Howat,Kiran Guttula,Richard A. Miller,Nicola S Fearnhead,Douglas J. Winton,Andre Tiago-Marques Neves,Kevin M. Brindle +10 more
TL;DR: The decreased binding of WGA and HPA to the luminal surface epithelium in human dysplasia suggests that these lectins may enable more sensitive detection of disease in the clinic using fluorescence colonoscopy.
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