Sarah C. Thomasset
University of Leicester
12 Papers
117 Citations
Sarah C. Thomasset is an academic researcher from University of Leicester. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 6, co-authored 7 publications. Previous affiliations of Sarah C. Thomasset include Leicester General Hospital & Leicester Royal Infirmary.
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Papers
Dietary polyphenolic phytochemicals—promising cancer chemopreventive agents in humans? A review of their clinical properties
Sarah C. Thomasset,David P. Berry,Giuseppe Garcea,Timothy H. Marczylo,William P. Steward,Andreas J. Gescher +5 more
TL;DR: A review of pilot studies and trials with a cancer chemoprevention‐related rationale, in which either healthy individuals or patients with premalignant conditions or cancer received polyphenolic phytochemicals is presented.
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Pilot study of oral anthocyanins for colorectal cancer chemoprevention.
Sarah C. Thomasset,David P. Berry,Hong Cai,Kevin West,Tim Marczylo,Debbie Marsden,Karen Brown,Ashley R. Dennison,Giuseppe Garcea,Andrew S. Miller,David Hemingway,William P. Steward,Andreas J. Gescher +12 more
TL;DR: Repeated administration of bilberry anthocyanins exerts pharmacodynamic effects and generates concentrations of anthOCyanins in humans resembling those seen in ApcMin mice, a model of FAP adenomas sensitive to the chemopreventive properties of anthcyanins.
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Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
Sarah C. Thomasset,Nicole Teller,Hong Cai,Doris Marko,David P. Berry,William P. Steward,Andreas J. Gescher +6 more
TL;DR: In the light of their robust cancer chemopreventive efficacy in experimental models and their superior stability as compared to that of the aglycons, the Anthocyanins seem much more suitable for further drug development than their anthocyanidin counterparts.
Malignant biliary strictures in patients with a normal bilirubin and/or normal liver enzymes
TL;DR: This study has shown that patients with a putative biliary stricture and completely normal LFTs are unlikely to have a primary HPB malignancy, and those presenting with a normal bilirubin level, but deranged liver enzymes (ALP and/or ALT), are more likely to have malignant disease, and this should necessitate a higher degree of clinical suspicion.
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Changing trends in the presentation of colorectal liver metastases in a single hepatobiliary tertiary referral centre over fourteen years
Sarah C. Thomasset,Ashley R. Dennison,Matthew S. Metcalfe,William P. Steward,Giuseppe Garcea +4 more
TL;DR: Investigating whether the time to presentation with colorectal liver metastases (CRLM) has changed over time suggests that CRC follow-up should be extended to 5 years.
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