Sara Samimi
University of Pennsylvania
39 Papers
117 Citations
Sara Samimi is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Medicine & Mycosis fungoides. The author has an hindex of 10, co-authored 32 publications. Previous affiliations of Sara Samimi include Children's Hospital of Philadelphia.
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Papers
Increased programmed death-1 expression on CD4+ T cells in cutaneous T-cell lymphoma: implications for immune suppression.
Sara Samimi,Bernice M. Benoit,Katherine G. Evans,E. John Wherry,Louise C. Showe,Maria Wysocka,Alain H. Rook +6 more
TL;DR: The data imply that increased PD-1 expression in Sézary syndrome may play a role in attenuating the immune response and provide further insight into the immunosuppressive nature of CD4(+) T cells in SÉzary Syndrome and suggest another potential means of targeted therapy for these patients.
145
Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphomas: reappraisal of a provisional entity in the 2016 WHO classification of cutaneous lymphomas
Joan Guitart,M. Estela Martinez-Escala,Antonio Subtil,Madeleine Duvic,Melissa Pulitzer,Elise A. Olsen,Ellen Kim,Alain H. Rook,Sara Samimi,Gary S. Wood,Michael Girardi,Jacqueline M. Junkins-Hopkins,Doina Ivan,M. Angelica Selim,Kimberly A. Sable,Pooja Virmani,Laura B. Pincus,Michael T. Tetzlaff,Jinah Kim,Youn H. Kim +19 more
TL;DR: The experience confirms the poor prognosis of this entity and highlights the inefficacy of standard therapies with the exception of allogeneic stem cell transplantation in selected cases.
92
High clinical response rate of Sezary syndrome to immunomodulatory therapies: prognostic markers of response.
Brian A. Raphael,Daniel B. Shin,Karen Rebecca Suchin,Kelly A. Morrissey,Carmela C. Vittorio,Ellen J. Kim,Jennifer M. Gardner,Katherine G. Evans,Camille E. Introcaso,Sara Samimi,Joel M. Gelfand,Alain H. Rook +11 more
TL;DR: A lower CD4/CD8 ratio, a higher percentage of monocytes, and lower numbers of circulating abnormal T cells at baseline were the strongest predictive factors for complete response compared with nonresponse and warrant further examination in a larger cohort.
40
Neonatal outcome after exposure to indomethacin in utero: a retrospective case cohort study
TL;DR: Indomethacin exposure was not associated with increased neonatal complications for infants delivered within or beyond 48 hours of last exposure, and the incidence of respiratory distress syndrome, need for surfactant treatment, patent ductus arteriosus, necrotizing enterocolitis, and intraventricular hemorrhage was similar.
31
Peripheral blood findings in erythrodermic patients: Importance for the differential diagnosis of Sézary syndrome
Arielle R. Nagler,Sara Samimi,Andras Schaffer,Carmela C. Vittorio,Ellen J. Kim,Alain H. Rook +5 more
TL;DR: Current data is evaluated on the usefulness and limitations of specific peripheral blood markers detected by flow cytometry and T-cell receptor gene rearrangement polymerase chain reaction in Sézary syndrome.
31