Sara Kreimer
Stanford University
5 Papers
Sara Kreimer is an academic researcher from Stanford University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 1 publications.
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Papers
Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening
Grant L. Lin,Kelli M. Wilson,Michele Ceribelli,Benjamin Z. Stanton,Pamelyn Woo,Sara Kreimer,Elizabeth Y. Qin,Xiaohu Zhang,James Lennon,Surya Nagaraja,Patrick J. Morris,Michael Quezada,Shawn M. Gillespie,Damien Y. Duveau,Aleksandra M. Michalowski,Paul Shinn,Rajarshi Guha,Marc Ferrer,Carleen Klumpp-Thomas,Sam Michael,Crystal McKnight,Paras S. Minhas,Zina Itkin,Eric H. Raabe,Lu Chen,Reem A. Ghanem,Anna Geraghty,Lijun Ni,Katrin I. Andreasson,Nicholas A Vitanza,Katherine E. Warren,Craig J. Thomas,Michelle Monje +32 more
TL;DR: This study provides a comprehensive single-agent and combinatorial drug screen for DMG and identifies concomitant HDAC and proteasome inhibition as a promising therapeutic strategy that underscores underrecognized metabolic vulnerabilities in DMG.
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Case Report: Castleman Disease With an Associated Stromal Spindle Cell Proliferation, PDGFRB Mutation and p53 Expression: Clonal Origins of a Rare Disease
K. Singh,Sumanth Gollapudi,Jyoti Kumar,Alexandra Butzmann,Corinn Small,Sara Kreimer,E. Arzu Saglam,Roger A. Warnke,o Pedro Silva,Robert S. Ohgami +9 more
TL;DR: An index case with morphology consistent with the hyaline vascular subtype of UCD with concomitant atypical smooth muscle actin (SMA)-positive stromal spindle cell proliferation containing a recurrent PDGFRB N666S mutation and upregulation of p53 expression is described.
Leiomyomatosis in an Infant With a SUFU Splice Site Variant: Case Report
Rameshwar R. Rao,Ben W. Dulken,Dena R. Matalon,M. Borensztein,Molly McGuinness,Stephanie Cizek,Matias Bruzoni,S.Y. Tan,Sara Kreimer +8 more
TL;DR: A 5-month-old female who presented with multiple intra-abdominal leiomyomata and was found to have a likely pathogenic splice site variant in the SUFU gene is described, which may represent an early, atypical presentation of Gorlin syndrome.
Quality of cancer family history taking in pediatric solid tumor patients.
Benjamin D Hu,Molly A. McGuinness,Adrienne Wakeling,Sara Kreimer,Jacquelyn Crane,Arun Rangaswami,Sheri L. Spunt +6 more
TL;DR: In this article , the ASCO guidelines recommend reviewing family history (FHx) to identify high-risk patients who should be offered genetic testing, however, to the best of our knowledge, adherence to these guidelines by pediatric oncology providers has not been studied.
1558 Global proteomic evaluation reveals longitudinal molecular skin improvements in atopic dermatitis patients treated with dupilumab
Elena Goleva,Evgeny Berdyshev,Robert Bissonnette,Sara Kreimer,Taras Lyubchenko,Shantanu Bafna,Inoncent Agueusop,Noah A. Levit,A. Zhang,Donald Y.M. Leung +9 more
TL;DR: In this paper , the results showed significant improvement in the expression of proteins involved in epidermal differentiation, normalization of lamellae assembly and antioxidant defense by 16 weeks of treatment, suggesting that these proteins are under control of T2 cytokines in AD skin.