4 Papers
1 Citations
Sara Evke is an academic researcher from State University of New York Polytechnic Institute. The author has contributed to research in topics: Selenocysteine & Translation (biology). The author has an hindex of 2, co-authored 4 publications. Previous affiliations of Sara Evke include State University of New York System & University at Albany, SUNY.
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Papers
Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins
TL;DR: The role of epitranscriptomic systems in post-transcriptional regulation is highlighted, with a specific focus on RNA modifying writers required for the incorporation of the 21st amino acid selenocysteine during translation, and the pathologies linked to epitranscriptionomic and selenoprotein defects.
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The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene.
Andrea Leonardi,Nataliia Kovalchuk,Lei Yin,Lauren Endres,Lauren Endres,Sara Evke,Steven Nevins,Samuel Martin,Peter C. Dedon,Peter C. Dedon,J. Andres Melendez,J. Andres Melendez,Laura S. Van Winkle,Qing Yu Zhang,Xinxin Ding,Thomas J. Begley +15 more
TL;DR: It is concluded that the epitranscriptomic writer ALKBH8 plays a protective role against naphthalene-induced lung dysfunction and promotes naphthaene tolerance, and provides an early example of how epitranscriptionomic systems can regulate the response to environmental stress in vivo.
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Epitranscriptomic reprogramming is required to prevent stress and damage from acetaminophen
TL;DR: In this article, the authors define how acetaminophen (APAP) induces epitranscriptomic reprogramming and how the writer Alkylation Repair Homolog 8 (Alkbh8) plays a key gene regulatory role in the response.
Epitranscriptomic regulation of the response to the air pollutant naphthalene in mouse lungs: From the perspectives of specialized translation and tolerance linked to the writer ALKBH8
Andrea Leonardi,Nataliia Kovalchuk,Lei Yin,Lauren Endres,Lauren Endres,Sara Evke,Steven Nevins,Samuel Martin,Peter C. Dedon,Peter C. Dedon,J. Andres Melendez,J. Andres Melendez,Laura S. Van Winkle,Qing Yu Zhang,Xinxin Ding,Thomas J. Begley +15 more
TL;DR: It is concluded that the epitranscriptomic writer ALKBH8 plays a protective role against NA-induced lung dysfunction and promotes NA tolerance, providing an early example of how epitranscriptionomic systems can regulate the response to environmental stress in vivo.