Sara Contente
Uniformed Services University of the Health Sciences
15Ā Papers
210Ā Citations
Sara Contente is an academic researcher from Uniformed Services University of the Health Sciences. The author has contributed to research in topics: Lysyl oxidase & Gene. The author has an hindex of 10, co-authored 15 publications.
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Papers
A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25.
TL;DR: A novel human cDNA with a predicted protein homologous to the carboxyl end of lysyl oxidase, an extracellular enzyme involved in the maturation of collagen and elastin, has been isolated.
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Epigenetic inhibition of lysyl oxidase transcription after transformation by ras oncogene.
TL;DR: The promoter activity of the lysyl oxidase reporter gene construct was completely abolished by in vitroDNA methylation, suggesting that the transcriptional suppression after transformation by the ras oncogene may involve DNA methylation.
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Structure of the mouse lysyl oxidase gene.
TL;DR: Primer extension and ribonuclease protection experiments revealed two sites of transcription initiation in a region with sequence motifs characteristic of a promoter, which was upstream and adjacent to the 5' untranslated sequence found in the cDNA.
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Treatment of Hepatitis C Infections with Interferon: A Historical Perspective
Robert M. Friedman,Sara Contente +1 more
TL;DR: Clinicians now have an excellent understanding of the basis for the effectiveness of interferon alpha (IFN-Ī±) in the therapy of hepatitis C virus infections, and treatment of HCV with IFN- Ī± may involve new anti-HCV agents that are currently under development.
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Reversion by Deletion of Transforming Oncogene Following Interferon-Ī² and Retinoic Acid Treatment
TL;DR: This paper showed that prolonged interferon-Ī²} (IFN-Ī²) treatment of RS485 cells (NIH3T3 cells transformed with multiple copies of an LTR-cHa-ras oncogene) resulted in the phenotypic reversio...
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