Sanna Aalto
Helsinki University Central Hospital
9 Papers
61 Citations
Sanna Aalto is an academic researcher from Helsinki University Central Hospital. The author has contributed to research in topics: Transplantation & Viral load. The author has an hindex of 8, co-authored 9 publications. Previous affiliations of Sanna Aalto include University of Helsinki.
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Papers
Epstein-Barr Viral Load and Disease Prediction in a Large Cohort of Allogeneic Stem Cell Transplant Recipients
Sanna Aalto,Eeva Juvonen,Jussi Tarkkanen,Liisa Volin,Heikki Haario,Tapani Ruutu,Klaus Hedman +6 more
TL;DR: High EBV DNA levels (i.e., >50,000 copies/mL) are strong predictors for the development of posttransplantation lymphoproliferative disease, are not spontaneously reversible, and should be treated immediately.
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Lymphoproliferative disease after allogeneic stem cell transplantation--pre-emptive diagnosis by quantification of Epstein-Barr virus DNA in serum.
Sanna Aalto,Eeva Juvonen,Jussi Tarkkanen,Liisa Volin,Tapani Ruutu,Petri S. Mattila,Heli Piiparinen,Sakari Knuutila,Klaus Hedman +8 more
TL;DR: Intensely immunosuppressed stem-cell recipients are at a great risk of developing PTLD, and should be carefully monitored for EBV-DNA, for pre-emptive treatment of this life-threatening disorder.
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Retrospective evaluation of serum Epstein Barr virus DNA levels in 406 allogeneic stem cell transplant patients.
TL;DR: EBV reactivation was a common phenomenon in allogenic stem cell transplant recipients and in many patients the viremia resolved without EBV-directed treatment.
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Monitoring of EBV-DNAemia by quantitative real-time PCR after adult liver transplantation
Raisa Loginov,Sanna Aalto,Heli Piiparinen,Leena Halme,Johanna Arola,Klaus Hedman,Krister Höckerstedt,Irmeli Lautenschlager +7 more
TL;DR: Low-level EBV-DNAemia is common after liver transplantation, often occurring together with betaherpesviruses, but seldom leads to high viral loads or PTLD, however, monitoring of EBv-DNA levels in the patients can be useful.
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Malignancies after heart transplantation: presence of Epstein-Barr virus and cytomegalovirus.
Petri S. Mattila,Sanna Aalto,Heikkilä L,Severi Mattila,Markku S. Nieminen,Eeva Auvinen,Klaus Hedman,Jussi Tarkkanen +7 more
TL;DR: The results confirm the presence of EBV in lymphomas of heart transplant recipients and suggest that CMV might have a contributory role in the development ofEBV‐associated lymphomas.
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